Molecular shape descriptors. 3. Steric mapping of biological receptor was written by Motoc, I.;Marshall, G. R.;Labanowski, J.. And the article was included in Zeitschrift fuer Naturforschung, Teil A: Physik, Physikalische Chemie, Kosmophysik in 1985.HPLC of Formula: 34662-36-7 This article mentions the following:
An improved version of the SIBIS algorithm is presented and illustrated. SIBIS is a self-consistent type algorithm which is well suited to delineate the main steric features of the biol. receptor, identify missing relevant atoms and(or) the presence of superfluous atoms in the mols. studied, and to provide an approx. estimate for the receptor bulk tolerance. SIBIS calculations for a set of substituted benzoates in the anti-p-(p‘-azophenylazo)benzoate antibody system yield an excellent QSAR which is further supported by the information correlation coefficients, R (R‘s express quant. the pairwise degree of the mol. shape relatedness); the optimal receptor steric map is in agreement with exptl. evidences. In the experiment, the researchers used many compounds, for example, 3-Chloro-5-nitrobenzoic acid (cas: 34662-36-7HPLC of Formula: 34662-36-7).
3-Chloro-5-nitrobenzoic acid (cas: 34662-36-7) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).HPLC of Formula: 34662-36-7
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics