Comparison of Different Polymer- and Silica-Supported 9-Amino-9-deoxy-epi-quinines as Recyclable Organocatalysts was written by Porta, Riccardo;Coccia, Francesca;Annunziata, Rita;Puglisi, Alessandra. And the article was included in ChemCatChem in 2015.Safety of Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) This article mentions the following:
9-Amino-9-deoxy-epi-quinine, properly modified by suitable linkers, was anchored on highly cross-linked polystyrene, poly(ethylene glycol), and silica. The resulting species were characterized by NMR spectroscopy and tested as supported organocatalysts in the reaction between isobutyric aldehyde and trans-尾-nitrostyrene. Polystyrene- and poly(ethylene glycol)-supported catalysts outperformed their nonsupported counterpart affording the desired product in high yield and ee (>90 % ee). Silica-supported catalysts proved to be less efficient in terms of both chem. yield and enantioselectivity. Polystyrene- and poly(ethylene glycol)-supported 9-amino-9-deoxy-epi-quinine were then used in the same reaction with different substrates, leading to the desired products in high yield and ee, as well as in three other reactions operating with different mechanism. An investigation of the recyclability of the polystyrene- and poly(ethylene glycol)-supported systems showed that these could be recovered and recycled with no loss of stereochem. activity but with a marked erosion of chem. efficiency occurring at the fifth reaction cycle. This was ascribed to chem. degradation of the alkaloid occurring during the reaction. In the experiment, the researchers used many compounds, for example, Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) (cas: 12083-92-0Safety of Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II)).
Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) (cas: 12083-92-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Safety of Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II)
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics