Determination of Three Endocrine Disruptors in Water Samples by Ultrasound-Assisted Salt-Induced Liquid-Liquid Microextraction (UA-SI-LLME) and High-Performance Liquid Chromatography – Diode Array Detection (HPLC-DAD) was written by Rozaini, Muhammad Nur’ Hafiz;Saad, Bahruddin;Yahaya, Noorfatimah;Lim, Jun Wei;Mohd Aris, Muhammad Naeim;Ramachandran, Muggundha Raoov. And the article was included in Analytical Letters in 2022.Name: 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea This article mentions the following:
Endocrine-disrupting compounds are routinely detected in environmental water. In this study, a simple and rapid sample preparation method based on ultrasound-assisted salt-induced liquid-liquid microextraction (UA-SI-LLME) followed by high performance liquid chromatog. – diode array detection (HPLC-DAD) was developed for the determination of triclosan, triclocarban and methyl-triclosan in water. Parameters that affect the extraction efficiency – such as type and mass of salt, type and volume of extraction solvent, extraction time, sample pH and sample volume – were studied. Under the optimized conditions, the method demonstrated linearity from 0.18 to 1000渭g L-1 with coefficients of determination R2 鈮?0.9899, limits of detection from 0.05 to 0.2渭g L-1, and good recoveries (> 70%) with relative standard deviations < 10%. The method was applied for the determination of triclosan, triclocarban, and methyl-triclosan in swimming pool, lake, and wastewater. The greenness of the method was quantified using the Anal. Eco-Scale Index. In the experiment, the researchers used many compounds, for example, 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea (cas: 101-20-2Name: 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea).
1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea (cas: 101-20-2) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Name: 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics