Synthesis of 1-aryl- and 1-alkyl-2,3-dimethylquinoxalinium perchlorates. Part 3. Synthesis of 1,2,3-trimethyl-6-X- and 1-cyclohexyl-2,3-dimethyl-6-X-quinoxalinium perchlorates was written by Schelz, D.;Rotzler, N.. And the article was included in Dyes and Pigments in 1983.Safety of Ethyl 4-chloro-3-nitrobenzoate This article mentions the following:
The title compounds (I; R = cyclohexyl, Me; R1 = H2N, MeO, Me, AcNH, H, halogen, EtO2C, F3C, MeSO2, O2N), useful as precursors for naphthophenazinone dyes were synthesized starting with 2-nitrohalobenzenes. The preferred method of condensing the diamine intermediate (II) with 2,3-butanedione聽聽[431-03-8] in mixtures of HOAc and HClO4 was not successful whenever R1 was a strongly electron-withdrawing substituent. But in those cases R1 stabilized the corresponding enamines III, which could be obtained very easily. In the experiment, the researchers used many compounds, for example, Ethyl 4-chloro-3-nitrobenzoate (cas: 16588-16-2Safety of Ethyl 4-chloro-3-nitrobenzoate).
Ethyl 4-chloro-3-nitrobenzoate (cas: 16588-16-2) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Safety of Ethyl 4-chloro-3-nitrobenzoate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics