Enol-keto tautomerism of 伪-ketophosphonates was written by Tam, Coretta C.;Mattocks, Karen L.;Tishler, Max. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 1981.HPLC of Formula: 6834-42-0 This article mentions the following:
R1CHR2COP(O)(OEt)2 (I; R1 = H, R2 = Me, CMe3, Ph, o-, m-, p-MeOC6H4, 3,4-(MeO)2C6H3, p-O2NC6H4; R1 = R2 = Me) were prepared in 60-90% yield by reaction of R1CHR2COCl with P(OEt)3; the keto-enol tautomerism of I was studied by proton and P NMR and IR and the FeCl3 test. Aliphatic I existed largely in the keto tautomeric forms, with only a small amount of enol forms present; however, aromatic I enolized extensively. Reaction of I (R1 = H, R2 = p-MeOC6H4) with CH2N2 gave a mixture of O-methylation and carbene insertion products; similar reaction of I (R1 = R2 = Me) gave only carbene insertion products. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0HPLC of Formula: 6834-42-0).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.HPLC of Formula: 6834-42-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics