Multi-functional multi-valency: a focused library of polymeric cholera toxin antagonists was written by Tran, Huu-Anh;Kitov, Pavel I.;Paszkiewicz, Eugenia;Sadowska, Joanna M.;Bundle, David R.. And the article was included in Organic & Biomolecular Chemistry in 2011.Recommanded Product: 3-Cyanobenzoyl chloride This article mentions the following:
Structural pre-organization of the multivalent ligands is important for successful interaction with multimeric proteins. Polymer-based hetero-bifunctional ligands that contain pendant groups prearranged into hetero-dimers can be used to probe the active site and surrounding area of the receptor. Here we describe the synthesis and activities of a series of galactose conjugates on polyacrylamide and dextran. Conjugation of a second fragment resulted in nano-molar inhibitors of cholera toxin, while the galactose-only progenitors showed no detectable activity. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1Recommanded Product: 3-Cyanobenzoyl chloride).
3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Recommanded Product: 3-Cyanobenzoyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics