Synthesis of biaryls via intramolecular free radical ipso-substitution reactions was written by Ujjainwalla, Feroze;da Mata, Maria Lucilia E. N.;Pennell, Andrew M. K.;Escolano, Carmen;Motherwell, William B.;Vazquez, Santiago. And the article was included in Tetrahedron in 2015.Application of 63624-28-2 This article mentions the following:
A variety of functionalized biaryls and heterobiaryls are prepared by intramol. free radical [1,5]-ipso-substitution using sulfonamide and sulfonate derived tethering chains. The overall efficiency of the process is determined by appropriately positioned substituents on the aromatic acceptor ring. The extension of the process to benzylic sulfonates and their corresponding N-methylsulfonamide alternatives as substrates in potential [1,6]-ipso-substitution reactions leads mainly to the alternative [1,7] addition products. In the experiment, the researchers used many compounds, for example, 2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2Application of 63624-28-2).
2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Application of 63624-28-2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics