The organocatalytic enantiodivergent fluorination of 尾-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters was written by Xie, Shaolei;He, Zhi-Juan;Zhang, Ling-Hui;Huang, Bo-Lun;Chen, Xiao-Wei;Zhan, Zong-Song;Zhang, Fu-Min. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2021.Synthetic Route of C9H9ClO2 This article mentions the following:
Com. available cinchona alkaloids that can catalyze the enantiodivergent fluorination of 尾-ketodiarylphosphine oxides were developed to construct carbon-fluorine quaternary stereocenters. This protocol features a wide scope of substrates and excellent enantioselectivities, and it is scalable. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Synthetic Route of C9H9ClO2).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Synthetic Route of C9H9ClO2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics