Wang, Qian; Mgimpatsang, Kumchok C.; Konstantinidou, Markella; Shishkina, Svitlana V.; Doemling, Alexander published the artcile< 1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction>, Product Details of C8H4ClF3O2, the main research area is oxadiazole aminoalkyl metal free multicomponent preparation; Ugi reaction amine aldehyde azidotrimethylsilane isonitrile; Huisgen reaction aminoalkyl tetrazole acyl chloride pyridine solvent.
Amines, aldehydes, Me3SiN3, and tert-octyl isonitrile t-BuCH2CMe2N+C- underwent Ugi reactions to yield aminoalkyltetrazoles such as I; acid cleavage of the tert-octyl group followed by Huisgen reactions with acyl chlorides in pyridine yielded oxadiazoles such as II.
Organic Letters published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 162046-61-9 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H4ClF3O2, Product Details of C8H4ClF3O2.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics