Jing, Ke; Wei, Ming-Kai; Yan, Si-Shun; Liao, Li-Li; Niu, Ya-Nan; Luo, Shu-Ping; Yu, Bo; Yu, Da-Gang published the artcile< Visible-light photoredox-catalyzed carboxylation of benzyl halides with CO2: Mild and transition-metal-free>, Application In Synthesis of 611-19-8, the main research area is aryl acetic acid preparation visible light; benzyl chloride bromide carbon dioxide carboxylation photoredox catalyst.
The visible-light photoredox-catalyzed carboxylation of benzyl chlorides and bromides with CO2 has been reported. With inexpensive organic dyes as photocatalysts and amines as electron donors, this carboxylation proceeds well in the absence of sensitive organometallic reagents, transition metal catalysts, or metallic reductants. A wide range of com. available and inexpensive benzyl halides undergo such carboxylation to give valuable aryl acetic acids, including several pharmaceutical mols. and drug precursors, in moderate to high yields. Moreover, this reaction features mild reaction conditions (one atm. pressure of CO2 and room temperature), broad substrate scope, good functional group tolerance, easy scalability, and low catalyst loading, thus providing an efficient approach for the assembly of aryl acetic acids.
Chinese Journal of Catalysis published new progress about Benzyl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 611-19-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2, Application In Synthesis of 611-19-8.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics