SDS of cas: 768-35-4In 2020 ,《Static to inducibly dynamic stereocontrol: The convergent use of racemic β-substituted ketones》 was published in Science (Washington, DC, United States). The article was written by DeHovitz, Jacob S.; Loh, Yong Yao; Kautzky, Jacob A.; Nagao, Kazunori; Meichan, Andrew J.; Yamauchi, Motoshi; MacMillan, David W. C.; Hyster, Todd K.. The article contains the following contents:
The synthesis of stereochem. complex mols. in the pharmaceutical and agrochem. industries requires precise control over each distinct stereocenter, a feat that can be challenging and time consuming using traditional asym. synthesis. Although stereoconvergent processes have the potential to streamline and simplify synthetic routes, they are currently limited by a narrow scope of inducibly dynamic stereocenters that can be readily epimerized. Here, we report the use of photoredox catalysis to enable the racemization of traditionally static, unreactive stereocenters through the intermediacy of prochiral radical species. This technol. was applied in conjunction with biocatalysts such as ketoreductases and aminotransferases to realize stereoconvergent syntheses of stereodefined β-substituted alcs. and amines from β-substituted ketones. After reading the article, we found that the author used (3-Fluorophenyl)boronic acid(cas: 768-35-4SDS of cas: 768-35-4)
(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.SDS of cas: 768-35-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics