Wu, Xiaofang; Zhou, Lei; Yang, Ruoqi; Guo, Fengzhe; Tang, Zi-Long; Xiao, Jing published the artcile< A practical chlorination of tert-butyl esters with PCl3 generating acid chlorides>, SDS of cas: 17082-09-6, the main research area is acid chloride preparation; tert butyl ester phosphorus trichloride chlorination.
For the first time, using PCl3, a range of tert-Bu esters is chlorinated successfully, allowing access of both aromatic acid chlorides and aliphatic acid chlorides RCOCl (R = Ph, 4-FC6H4, 4-MeC6H4, etc.) in good yields. The method features simple reaction conditions and wide substrate scope. Various tert-Bu esters including aryl esters, alkenyl esters, and alkyl esters were tolerated well in the reaction. A plausible mechanism is proposed.
Journal of Chemical Research published new progress about Acid chlorides Role: SPN (Synthetic Preparation), PREP (Preparation). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, SDS of cas: 17082-09-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics