Borra, Satheesh; Chae, Soyeon; Kim, Hun Young; Oh, Kyungsoo published the artcile< Continuous Flow Synthesis of 1,4-Benzothiazines Using Ambivalent Reactivity of (E)-β-Chlorovinyl Ketones: A Point of Reaction Control Enabled by Flow Chemistry>, Computed Properties of 17082-09-6, the main research area is benzothiazine preparation diastereoselective flow; chlorovinyl ketone dithiodianiline cyclization.
A continuous flow system to 1,4-benzothiazines I (R = H, OMe, Cl, Br, CF3; R1 = H; RR1 = -CH=CH-CH=CH-; R2 = n-Bu, Ph, Bn, 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl, etc.; R3 = Ph, 4-chlorophenyl, furan-2-yl, benzo[d][1,3]dioxol-5-yl, etc.) was developed using the point of reaction control, where the ambivalent (E)-β-chlorovinyl ketones R1CH2C(Cl)=CHC(O)R2 and 2,2′-dithiodianilines II were confined in a diffusion controlled flow setting. The successful segregation of reactive chem. species in a flow setting allowed more defined reaction pathways that are not feasible in traditional batch reaction conditions. The point of reaction control in flow systems helps to execute the reactions often plagued with the concurrent generation of multiple chem. species.
Organic Letters published new progress about Benzothiazines Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Computed Properties of 17082-09-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics