Electric Literature of 2732-80-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2732-80-1, name is 2-Bromo-1-chloro-4-methoxybenzene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
BBr3 (50 ml) was added slowly in drops over 15 minutes to a solution of 2-bromo-l- chloro-4-methoxybenzene (0.448 mol) in CH2Cl2 (600 ml), stirred at -2O0C. The resultant reaction mixture was stirred for 20 minutes at -200C, then it was warmed to room temperature and stirred for one hour at room temperature, yielding 85 g of intermediate (75).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Bromo-1-chloro-4-methoxybenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; JANSSEN PHARMACEUTICA NV; WO2009/62990; (2009); A2;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics