Synthetic Route of C6H6BFO2In 2021 ,《Access and modulation of substituted 1-methyl-1,6-dihydropyrazolo[3,4-c]pyrazoles》 appeared in RSC Advances. The author of the article were Ostache, Nicu-Cosmin; Hiebel, Marie-Aude; Finaru, Adriana-Luminita; Allouchi, Hassan; Guillaumet, Gerald; Suzenet, Franck. The article conveys some information:
A convenient design of new pyrazolo[3,4-c]pyrazoles I (R = C6H5, 4-OCH3-C6H4, 4-CF3-C6H4; R1 = H, Br, Ph, 3-thiophene, 4-pyridine, styril, etc.) with a high therapeutic impact has been described. The effective chosen strategy consists of hydrazine condensations and C-N Ullmann-type cross-coupling reactions with microwave activation. Moreover, chemoselective bromination of the newly formed bipyrazoles followed by Suzuki-Miyaura cross-coupling reactions allowed the synthesis of a variety of modulated heterobicycles. In the experiment, the researchers used many compounds, for example, (3-Fluorophenyl)boronic acid(cas: 768-35-4Synthetic Route of C6H6BFO2)
(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Synthetic Route of C6H6BFO2
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