Chloride substituents modify the physical properties of organic compounds in several ways. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Application of C6H4BrClO2S.
Luo, Xu;Wang, Shengchun;Lei, Aiwen research published 《 Electrochemical-Induced Hydroxysulfonylation of α-CF3 Alkenes to Access Tertiary β-Hydroxysulfones》, the research content is summarized as follows. An electrochem. hydroxysulfonylation of α-CF3 alkenes RC(=CH2)CF3 (R = 4-CH3OC6H4, 2,3-dihydro-1,4-benzodioxin-6-yl, naphthalen-2-yl, etc.) was accomplished in this work. By using easily available sodium sulfinates R1SO2Na (R1 = Me, Ph, cyclopropyl, etc.) as the sulfonylating agents, a series of valuable α-trifluoromethyl tertiary alcs. RC(OH)CF3CH2S(O)2R1 was synthesized under mild and environmentally friendly electrolysis conditions in moderate to good yields. The preliminary mechanistic investigation indicates that this difunctional reaction involves a radical process via a sulfonyl radical. Gram-scale synthesis shows the significant potential application of this protocol.
Application of C6H4BrClO2S, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics