Chlorinated organic compounds are found in nearly every class of biomolecules. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. SDS of cas: 2905-24-0.
Yu, Qiuyu;Zhang, Jinghang;Wu, Fan;Liu, Xiaoqin;Wang, Chang;Zhang, Jinpeng;Rong, Liangce research published 《 Propargyl Chalcones’ Radical Annulation/Sulfonation Reaction: Efficient Synthesis of Benzo[b]oxepin-5(2H)-one and Chromane Derivatives》, the research content is summarized as follows. A novel and facile methodol. for the synthesis of sulfonated benzo[b]oxepinones I (R = H, F, Br; R1 = H, MeO; R2 = Ph, 3-methoxyphenyl, 2-thienyl, etc.; Ar = Ph, 4-methylphenyl, 4-bromophenyl, etc.) and chromane derivatives II (R3 = H, MeO, F, Cl, Br; R4 = H, MeO; R3R4 = -CH=CH-CH=CH-; R5 = Ph, 2-fluorophenyl, 4-methylphenyl; Ar1 = Ph, 2-fluorophenyl, biphenyl-4-yl, etc.) was reported by the reaction of propargyl chalcones 3-R-4-R1-6-OCH2CCHC6H2C(O)CH=CHR2/3-R3-4-R4-6-OCH2CCHC6H2CH=CHC(O)R5 with arylsulfonyl chlorides Ar/Ar1SO2Cl via radical cascade annulation/sulfonation under laboratory conditions. Readily available propargyl chalcones, commercialized arylsulfonyl chlorides, and simple reaction conditions make this six(seven)-membered oxygen-containing heterocycles’ synthetic strategy more attractive and with significant application values.
2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., SDS of cas: 2905-24-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics