Warsitz, Michael published the artcileTwo-Step Procedure for the Synthesis of 1,2,3,4-Tetrahydro-quinolines, Related Products of chlorides-buliding-blocks, the main research area is chlorostyrene aniline alkyl titanium regioselective hydroaminoalkylation catalyst; amine aryl alkyl preparation palladium Buchwald Hartwig amination; tetrahydroquinoline preparation.
A new two-step procedure that includes an initial regioselective intermol. hydroaminoalkylation of ortho-chlorostyrenes with N-methylanilines and a subsequent intramol. Buchwald-Hartwig amination gives direct access to 1,2,3,4-tetrahydroquinolines. The hydroaminoalkylation reaction of the ortho-chlorostyrenes is catalyzed by a 2,6-bis(phenylamino)pyridinato titanium complex which delivers the linear regioisomers with high selectivities. In addition, the formation of unexpected dihydroaminoalkylation products from styrenes and N-methylanilines is reported.
European Journal of Organic Chemistry published new progress about Aminoalkylation (regioselective hydroaminoalkylation). 93118-03-7 belongs to class chlorides-buliding-blocks, name is 2-Chloro-3-(trifluoromethyl)benzaldehyde, and the molecular formula is C8H4ClF3O, Related Products of chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics