Ruso, Jayaraman Sembian published the artcileAntimicrobial activities of novel 3-substituted[1,2,4]triazolo[4,3-b]pyridazine derivatives, Application of 2-Chloro-3-(trifluoromethyl)benzaldehyde, the main research area is triazolopyridazine preparation antibacterial antifungal.
A novel derivatives of 3-substituted[1,2,4]triazolo[4,3-b]pyridazine I (R1 = 3-BrC6H4, 2-Br-6-ClC6H3, 2,6-Cl2C6H3, etc.) and 7,8,9,10-tetrahydrobenzo[4,5]thieno[2,3-d][1,2,4]triazolo[4,3-b]pyridazine II (R2 = 3-BrC6H4, 4-Br-C6H4, 2-F3CC6H4, etc.) were prepared by the reaction of heteroaryl hydrazone from the aldehyde and pyridazinohydrazine derivative, followed by subjecting the intermediate directly to oxidative cyclization employing the mixture of Me4NBr and oxone. These derivatives were subjected to preliminary antimicrobial activities against microorganism. All the compounds exhibited good to moderate activity.
Hwahak Sekye published new progress about Antibacterial agents. 93118-03-7 belongs to class chlorides-buliding-blocks, name is 2-Chloro-3-(trifluoromethyl)benzaldehyde, and the molecular formula is C8H4ClF3O, Application of 2-Chloro-3-(trifluoromethyl)benzaldehyde.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics