Dichlororesorufin-Based Colorimetric and Fluorescent Probe for Ultrasensitive Detection of Mercury Ions in Living Cells and Zebrafish was written by Duan, Qingxia;Lv, Xiaoyu;Liu, Caiyun;Geng, Zhuofan;Zhang, Fenfen;Sheng, Wenlong;Wang, Zuokai;Jia, Pan;Li, Zilu;Zhu, Hanchuang;Zhu, Baocun. And the article was included in Industrial & Engineering Chemistry Research in 2019.Category: chlorides-buliding-blocks The following contents are mentioned in the article:
In this work, a simple dichlororesorufin-based colorimetric and fluorescent probe R-Hg with the recognition receptor of carbonothioate was designed, synthesized, and exploited to determine mercury ions in aqueous solution and living cells as well as in zebrafish. After a series of anal. tests, probe R-Hg showed some excellent characteristics, such as ultrasensitivity, high selectivity, and good water solubility The probe solution exhibited a very large fluorescence enhancement (about 150-fold) upon addition of Hg2+. Addnl., probe R-Hg exhibited excellent sensitivity, which could quantificationally detect Hg2+ at the nanomolar level, and the detection limit was 0.49 nM. Moreover, probe R-Hg could be used as a “naked-eye” probe for monitoring Hg2+, because the color of its solution transformed remarkably from yellow into pink with the participation of Hg2+. Importantly, probe R-Hg has potential application value and has been successfully applied to the determination of Hg2+ in practical water samples and in living RAW 264.7 cells as well as in zebrafish as a bioimaging reagent. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Category: chlorides-buliding-blocks).
4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Category: chlorides-buliding-blocks
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics