Nucleophilic Cyclization/Electrophilic Substitution of (2,2-Dialkoxyethyl)ureas: Highly Regioselective Access to Novel 4-(Het)arylimidazolidinones and Benzo[d][1,3]diazepinones was written by Smolobochkin, Andrey V.;Gazizov, Almir S.;Otegen, Nazerke K.;Voronina, Julia K.;Strelnik, Anna G.;Samigullina, Aida I.;Burilov, Alexander R.;Pudovik, Michail A.. And the article was included in Synthesis in 2020.Recommanded Product: 4-Chlororesorcinol The following contents are mentioned in the article:
Herein, a highly regioselective acid-catalyzed intramol. nucleophilic cyclization/intermol. electrophilic substitution reaction sequence of (2,2-dialkoxyethyl)ureas was reported. The reaction benefits from readily available starting materials, a simple workup procedure, moderate to high yields of target compounds and provided a convenient entry to previously unknown 4-(het)arylimidazolidinones and 5-(het)arylbenzodiazepinones. The proposed mechanism of the reaction was also discussed. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Recommanded Product: 4-Chlororesorcinol).
4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Recommanded Product: 4-Chlororesorcinol
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics