Udovitskaya, V. V.’s team published research in Khimiko-Farmatsevticheskii Zhurnal in 4 | CAS: 38146-42-8

Khimiko-Farmatsevticheskii Zhurnal published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C10H12O5, Quality Control of 38146-42-8.

Udovitskaya, V. V. published the artcileSynthesis and antimicrobiol activity of ammonium derivatives of cyclohexane, Quality Control of 38146-42-8, the publication is Khimiko-Farmatsevticheskii Zhurnal (1970), 4(1), 17-20, database is CAplus.

Haloacetates (Ia) of substituted cyclohexanols, XCH2CO2R, were prepared by the method of Conrad (1877) as follows (R, X, b.p./mm, % yield, n20D, and d20 reported): 4-MeC6H10, Cl, 92-4°/5, 50.7, 1.4576, 1.0937; 4-MeC6H10, Br, 136-8°/30, 49.0, 1.4772, 1.3051; 3,3,5-Me3C6H8, Cl, 154-6°/50, 85.0, 1.4575, 1.0419; 3,3,5-Me3C6H8, Br, 156-8°/30, 71.4, 1.4717, 1.2152; menthyl, Cl, 132-4°/8, 41.0, 1.4625, 1.0420. Ia with tertiary amines in EtOH or Me2CO gave quaternary ammonium salts [ZNCH2CO2R]+X- (I). The following I derived from dl-menthol were reported (ZN, X, m.p., and % yield given): Me3N, Cl, 226°, 97; Et3N, Cl, 179°, 94; Et2NCH2CH2OH, Br, 144-6°, 94; Et2NCH2CH2O2CC6H4NH2-p, Cl, 89°, 83; C5H5N, Br, 173-4°, 86; 4-methylpyridine, Br, 196-7°, 81; quinolin e, Br, 197°, 78; 4-aminoquinaldine, Br, 169°, 73; N-methylmorpholine, Br, 161-2°, 74. An analogous reaction with tertiary diamines gave the following [RO2CCH2Me2N+(CH2)nN+Me2CH2CO2R]-2X- (R, n, X, m.p., and % yield given): 4-MeC6H10, 2, Br, 176-7°, 85; 3,3,5-Me3C6H6, 2, Br, 184-5 °, 93; 4-MeC6H10, 6, Br, 165-6°, 93; 4-MeC6H10, 6, Cl, 102-4°, 72; 3,3,5-Me3C6H8, 6, Br, 134-5°, 83; 3,3,5-Me3C6H8, 6, Cl, 110-12°, 66; C6H11, 10, Cl, 96-8°, 86; 4-MeC6H10, 10, Br, 82-5°, 85; 3,3,5-Me3C6H8, 10, Br, 92-4°, 82; 3,3,5-Me3C6H8, 10, Cl, 85-7°, 92; l-menthyl, 10, Br, 142°, 67; l-menthyl, 10, Cl, 167-8°, 92; dl-menthyl, 10, Cl, 116-18°, 56. All the quaternary salts prepared were tested in vitro against Staphylococcus aureus and Escherichia coli.

Khimiko-Farmatsevticheskii Zhurnal published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C10H12O5, Quality Control of 38146-42-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics