Pravardhan Reddy, E.’s team published research in Tetrahedron Letters in 97 | CAS: 939-99-1

Tetrahedron Letters published new progress about 939-99-1. 939-99-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzyl chloride,Benzene, name is 1-(Chloromethyl)-4-(trifluoromethyl)benzene, and the molecular formula is C8H6ClF3, Formula: C8H6ClF3.

Pravardhan Reddy, E. published the artcileBenzyl chlorides as aldehyde surrogates in the Prins cyclization: Direct access to 2-aryl-4-chlorotetrahydropyrans, Formula: C8H6ClF3, the publication is Tetrahedron Letters (2022), 153746, database is CAplus.

An efficient synthesis of 2-aryl-4-chloro-tetrahydropyrans was accomplished from benzyl chlorides and homoallylic alcs. using FeCl3 as a promoter through a sequential oxidation/Prins cyclization in high yields. This was the first report on the use of benzyl chlorides as surrogates for aldehydes in the Prins cyclization.

Tetrahedron Letters published new progress about 939-99-1. 939-99-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzyl chloride,Benzene, name is 1-(Chloromethyl)-4-(trifluoromethyl)benzene, and the molecular formula is C8H6ClF3, Formula: C8H6ClF3.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics