Amide Effects in C-H Activation: Noncovalent Interactions with L-Shaped Ligand for meta Borylation of Aromatic Amides was written by Bisht, Ranjana;Hoque, Emdadul Md;Chattopadhyay, Buddhadeb. And the article was included in Angewandte Chemie, International Edition in 2018.SDS of cas: 1711-11-1 This article mentions the following:
Borylated aromatic amides 3-pinBC6H4-nXnCONR2 (6a–t; X = halo, CN, Ph, benzo, MeO) were prepared by meta C-H activation/borylation of amides XnC6H5-nCONR2 with B2pin2, catalyzed by [Ir2(cod)2(渭-OMe)2]/L1 with up to 99% regioselectivity. A new concept for the meta-selective iridium-catalyzed borylation of aromatic amides is described. It has been demonstrated that while esters gave para-borylated products, amides lead to meta borylations. For achieving high meta selectivity, an L-shaped bifunctional ligand I (L1) has been employed and engages in an O…K noncovalent interaction with the oxygen atom of the moderately distorted amide carbonyl group. This interaction provides exceptional control for providing up to 99% selective formation of meta-borylated products. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1SDS of cas: 1711-11-1).
3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.SDS of cas: 1711-11-1
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics