Palladium-Catalyzed anti-Michael Reductive Heck Reaction of 伪,尾-Unsaturated Esters was written by Guo, Tao;Ding, Yalan;Zhou, Lili;Xu, Haiyan;Loh, Teck-Peng;Wu, Xiaojin. And the article was included in ACS Catalysis in 2020.HPLC of Formula: 206559-40-2 This article mentions the following:
A general intermol. anti-Michael reductive Heck reaction of 伪,尾-unsaturated esters with organobromides has been developed. Most topical classes of aryl, heteroaryl, and vinyl bromides were found to efficiently react with a variety of internal conjugated alkenes. This protocol set up a platform toward diverse 伪-arylated 1,6-dicarbonyl frameworks found in natural products and drugs, which are still highly challenging targets in traditional 伪-arylation protocols because of competitive selectivity of enolation. A removable directing group, gram-scale reaction, and modification of complex mols. have addnl. demonstrated that the anti-Michael reductive Heck reaction is a powerful complementary strategy to the classical 伪-arylation approaches. Preliminary mechanistic studies are consistent with our proposed mechanistic design. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-chloro-m-xylene (cas: 206559-40-2HPLC of Formula: 206559-40-2).
5-Bromo-2-chloro-m-xylene (cas: 206559-40-2) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.HPLC of Formula: 206559-40-2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics