Reference of 14862-52-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 14862-52-3, name is 3,5-Dibromochlorobenzene, This compound has unique chemical properties. The synthetic route is as follows.
Toluene (200 ml) and water (50 ml)Of (9,9-dimethyl-9H-fluorene -2-yl) boronic acid (5.0 g, 21.0 mmol), 1,3-dibromo-5-chlorobenzene (14.19 g, 52.5 mmol), Pd (PPh3 ) it is refluxed in a solution of 4 (0.49 g, 0.42 mmol), and K2CO3 (5.80 g, 42.0 mmol) under nitrogen for 18 hours. After cooling to room temperature (~ 22 ), isolating the organic layer it was distilled off excess 1,3-dibromo-5-chlorobenzene. The residue as eluent heptane / DCM (9/1, v / v) for purification by column chromatography on silica gel, and as a colorless crystalline solid 2- (3-bromo-5-chlorophenyl) -9, 9-dimethyl -9H- FluoreneTo give a (6.2 g, 77%).
The chemical industry reduces the impact on the environment during synthesis 3,5-Dibromochlorobenzene. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Universal Display Corporation; Cheng, Licang; Rayekh, Suman; Vaudreuil, Pierre Ruik-T; Elshennawy, Zaineb; Kottas, Greg; Diatkine, Alexei Borysovych; Joseph, Scott; Adamowicz, Vadim; Xia, Chuanjun; Wang, Ting Chiu; Jage, Walter; (109 pag.)KR2016/6633; (2016); A;,
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