Related Products of 57310-39-1, A common heterocyclic compound, 57310-39-1, name is 3-Bromo-4-chlorotoluene, molecular formula is C7H6BrCl, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
The title compound was prepared from 39 in the same manner as described for 33 (63% yield over two steps, a colorless oil).1H NMR (CDCl3) delta: 2.31 (3H, s), 3.58-3.90 (6H, m), 3.96 (1H, d, J = 10.6 Hz), 4.38 (1H, d, J = 10.4 Hz), 4.50-4.68 (3H, m), 4.78-4.98 (4H, m), 6.91-7.08 (3H, m), 7.12-7.38 (20H, m). MS (FAB) m/z: 649 (M++H), calcd for C41H41ClO5: 648.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Ikegai, Kazuhiro; Imamura, Masakazu; Suzuki, Takayuki; Nakanishi, Keita; Murakami, Takeshi; Kurosaki, Eiji; Noda, Atsushi; Kobayashi, Yoshinori; Yokota, Masayuki; Koide, Tomokazu; Kosakai, Kazuhiro; Ohkura, Yasufumi; Takeuchi, Makoto; Tomiyama, Hiroshi; Ohta, Mitsuaki; Bioorganic and Medicinal Chemistry; vol. 21; 13; (2013); p. 3934 – 3948;,
Chloride – Wikipedia,
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