Synthetic Route of 98-60-2,Some common heterocyclic compound, 98-60-2, name is 4-Chlorobenzenesulfonyl chloride, molecular formula is C6H4Cl2O2S, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: The substance was synthesized according to a previously reported procedure with some modifications.[3] To a stirred and warmed (80 oC) solution of Na2SO3 (2.36 g, 19 mmol) and NaHCO3 (1.68 g, 20 mmol) in 100 mL H2O was added portionwise arylsulfonyl chloride (10 mmol). The mixture was stirred at 90 C for 3 h, then filtered, and the filtrate concentrated under vacuum. The residue was recrystallised from water (5 mL) to yield the corresponding sodium arylsulfinate.
The synthetic route of 98-60-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Li, Xinxin; Chen, Fei; Lu, Guo-Ping; Tetrahedron Letters; vol. 59; 48; (2018); p. 4226 – 4230;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics