Related Products of 2106-02-7, These common heterocyclic compound, 2106-02-7, name is 2-Chloro-4-fluoroaniline, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: The aniline (1 eq, 0.0017 mol) was added to amixture of 5 (0.5g, 0.0017 mol), ethanol: water (7:3mL) and 4-5 drops of HCl (pH is 5-6). The reactionmixture was stirred for 4 hr at 65-70 0 . The reactionmixture was cooled to RT, a solid separated out whichwas filtered, washed with water (10 mL) and dried.The crude product was purified by recrystallizationfrom ethanol-water (2:1) to obtain pure 6.
The synthetic route of 2106-02-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Rajitha, Ch.; Vineel, B. George; Venkataiah; Dubey; Indian Journal of Heterocyclic Chemistry; vol. 24; 3; (2015); p. 325 – 328;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics