In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1435-48-9, name is 2,4-Dichloro-1-fluorobenzene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Formula: C6H3Cl2F
5.Og (30mmol) of 2, 4-dichloro-l-fluorobenzene was stirred in 40 ml of concentrated sulfuric acid under ice cooling, and 3.1g (30 mmol) of potassium nitrate was added to this stirring solution. The temperature was returned to room temperature, and the mixture was stirred for 12 hours, then, poured into ice water, and extracted with ethyl acetate. The organic layer was washed with water and saturated saline, then, dried over sodium sulfate, and the solvent was distilled off under reduced pressure to obtain 6.2 g (yield: 97%) of the aimed compound.
The synthetic route of 1435-48-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BAYER CROPSCIENCE AG; WO2007/131680; (2007); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics