Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1939-99-7, name is Phenylmethanesulfonyl chloride, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of Phenylmethanesulfonyl chloride
General procedure: Pyridine (73 lL, 0.90 mmol) and DMAP were added to a solution10a (203 mg, 0.7 mmol) in anhydrous DCM (10 mL). Then benzenesulfonylchloride (145 mg, 0.76 mmol) was dissolved in DCMand added dropwise under a nitrogen atmosphere. The reactionmixture was then stirred at room temperature for 1 day.Whereupon, HCl (1 mol/L) was added and the reaction mixturewas extracted with DCM. The organic phases were combined anddried over anhydrous Na2SO4. After removal of volatiles, a residuewas obtained that was then subjected to silica-gel column chromatographicpurification to afford this intermediate 13a (196 mg,63%).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1939-99-7.
Reference:
Article; Liu, Peihong; Du, Yongli; Song, Lianhua; Shen, Jingkang; Li, Qunyi; Bioorganic and Medicinal Chemistry; vol. 23; 21; (2015); p. 7079 – 7088;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics