Related Products of 328-84-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 328-84-7 name is 3,4-Dichlorobenzotrifluoride, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Example -4; 3,4-Dichlorobenzotrifluoride (75.4 g) was added to 210 g of dimethylsulfone 30.45 g of calcined potassium fluoride in an autoclave. The ammonia gas (1 to 1.2 m/m) was passed at 30¡ãC. The reaction mixture was maintained at 235¡ãC and pressure of 25-26 kg/cm for 6 hrs. After work up and fractionation the yield of 2-chloro-4-trifluoromethylaniline was 84percent based on 3,4-dichlorobenzotrifluoride consumed.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3,4-Dichlorobenzotrifluoride, and friends who are interested can also refer to it.
Reference:
Patent; GHARDA, Keki Hormusji; WO2011/107998; (2011); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics