14862-52-3, name is 3,5-Dibromochlorobenzene, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Formula: C6H3Br2Cl
Intermediate 1-2 (2.8 g, 0.010 mol) was added intermediate 1-3 (4.2 g, 0.011 mol),Pd (dba) 2 (0.5 g, 0.0005 mol), 100 mL of Toluene was added to sodium-tert-butoxide (1.9 g, 0.020 mol), and the mixture was reacted at 95 C. for 4 hours with stirring.After completion of the reaction, the mixture was separated into H 2 O: MC and purified by column (N-HEXANE: MC) to obtain 3.6 g (yield: 62%) of Intermediate 1-4. To 1,3-dibromo-5-chlorobenzene (2.7 g, 0.010 mol) was addedN-phenylbiphenyl-4-amine (5.4 g, 0.022 mol) was added to the reaction mixture to obtain 4.4 g (yield 73%) of Intermediate 7-1.
The synthetic route of 14862-52-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; P&H Tech Co.,Ltd; Hyun, Sao Yong; Jung, Sung Wook; Kim, Ha Yeon; (48 pag.)KR2016/79514; (2016); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics