Quality Control of 2-Chloro-6-methylaniline. Recently I am researching about ARYLATION; ALKYNES; INDOLOQUINOLINES; ACTIVATION; ACCESS; HYDROARYLATION; ANNULATION; ALKALOIDS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21901184, 21572160, 21702091]; Doctoral Program Foundation of Tianjin Normal University [043135202-XB1703]; Program for Innovative Research Team in University of Tianjin [TD13-5074]; Science&Technology Development Fund of Tianjin Education Commission for Higher Education [:2018KJ159]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Chen, C; Wang, YB; Shi, XN; Sun, W; Zhao, JH; Zhu, YP; Liu, LY; Zhu, BL. The CAS is 87-63-8. Through research, I have a further understanding and discovery of 2-Chloro-6-methylaniline
Here we report a protocol to synthesize diversiform fluorinated isocryptolepine analogues with potential biological activities in one step via directed C-2 and C-3 dual C-H functionalization of indoles. We also attempted to take into account fluorinated imidoyl chlorides as a novel kind of synthons in the directed C-H functionalization reactions. As a result, a variety of fluorinated isocryptolepine analogues were obtained in up to 96% yield. Moreover, we conducted control experiments to disclose the reaction mechanism.
Quality Control of 2-Chloro-6-methylaniline. About 2-Chloro-6-methylaniline, If you have any questions, you can contact Chen, C; Wang, YB; Shi, XN; Sun, W; Zhao, JH; Zhu, YP; Liu, LY; Zhu, BL or concate me.
Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
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