Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 622-24-2, name is (2-Chloroethyl)benzene, A new synthetic method of this compound is introduced below., Safety of (2-Chloroethyl)benzene
To a solution of substituted hydrazine (3 mmol) and carbon disulfide (8 mmol) Triton-B (2 mmol) were slowly added while stirring at room temperature. The stirring was continued till 0.5 h after which required amount of alkyl halide (3 mmol) was added (Scheme-I). The reaction was further continued until the completion of reaction (Table-1) under argon. The obtained mixture was poured into water (20 mL) and the extraction of organic layer was done with EtOAc (3 ¡Á 10 mL). The organic layer was washed with 0.1 N hydrochloric acid (20 mL), sodium bicarbonate solution (25 mL), brine solution (30 mL) and dried sodium sulfate and concentrated to get the desired compound I. Later, the desired compounds were confirmed by IR, NMR and elemental analysis.
The synthetic route of 622-24-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Zaidi, Sadaf; Saxena, Mridula; Asian Journal of Chemistry; vol. 31; 7; (2019); p. 1581 – 1584;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics