In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Rhodium(III)-Catalyzed Redox-Neutral 1,1-Cyclization of N-Methoxy Benzamides with Maleimides via C-H/N-H/N-O Activation: Detailed Mechanistic Investigation, published in 2019-04-05, which mentions a compound: 4144-22-3, mainly applied to rhodium catalyzed redox neutral cyclization methoxybenzamide maleimide spiroisoindolinone, HPLC of Formula: 4144-22-3.
An Rh(III)-catalyzed 1,1-cyclization of N-methoxy benzamides with maleimides providing isoindolinone spirosuccinimides through N-H/C-H/N-O bond activation is described. The detailed mechanistic investigation including isolation of key metalacycle intermediate, deuterium labeling studies, and DFT calculations were performed. The computational study reveals that the AcOH that formed in the reaction medium plays a key role in the N-OMe bond cleavage and the oxidation of Rh(I) to Rh(III).
After consulting a lot of data, we found that this compound(4144-22-3)HPLC of Formula: 4144-22-3 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics