Recommanded Product: 3,3′-Diindolylmethane. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 3,3′-Diindolylmethane, is researched, Molecular C17H14N2, CAS is 1968-05-4, about (Thio)urea-catalyzed Friedel-Crafts Reaction: Synthesis of Bis(indolyl)- methanes. Author is Rivas-Loaiza, Juan A.; Reyes-Escobedo, Carlos E.; Lopez, Yliana; Rojas-Lima, Susana; Garcia-Merinos, Juan Pablo; Lopez-Ruiz, Heraclio.
Bis(indolyl)methane derivatives (BIMs) were synthesized in moderate to good yields by (thio)urea catalyzed electrophilic substitution of indole with various aldehydes. Reactions were performed under conventional and microwave (MW) heating, either using 1,2-dichloroetane as solvent or without solvent. The procedure using microwave heating was also applied to the synthesis of the natural products vibrindole A, arsindoline A, arundine and tris(1H-indol-3-yl)methane. Addnl., the synthesis of streptindole was carried out via 2,2-bis(3-indolyl)acetic acid. This methodol. is well suited for the synthesis of bis(indolyl)methanes: it offers good yields of products, low sensitivity to moisture and oxygen, high tolerance to different functional groups on the aldehydes such as alkynes and trimethylsilane, and simplicity in operation.
The article 《(Thio)urea-catalyzed Friedel-Crafts Reaction: Synthesis of Bis(indolyl)- methanes》 also mentions many details about this compound(1968-05-4)Recommanded Product: 3,3′-Diindolylmethane, you can pay attention to it, because details determine success or failure
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