Chloride substituents modify the physical properties of organic compounds in several ways. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Safety of 2,3-Dichlorobenzaldehyde.
Jiang, Ling;Lu, Qingqing;Dong, Jingwen;Chu, Xiaohe research published 《 Mechano-biocatalytic rapid synthesis of 2-amino-3-cyano-4H-pyran derivatives》, the research content is summarized as follows. A series of 2-amino-3-cyano-4H-pyrans I (R1 = Ph, 2-FC6H4, 3-MeOC6H4, etc.) and II were synthesized in good to excellent yields via a simple one-pot reaction. The facile method depended on one-pot three-component reaction of aromatic aldehyde, malononitrile and dimedone or 3-(dimethylamino)phenol in the presence of bovine serum albumin (BSA) as the catalyst under ball-milling conditions. The reactions were completed in 40 min in 80-98% yields.
Safety of 2,3-Dichlorobenzaldehyde, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics