SDS of cas: 7791-11-9In 2021, Chen, Qian;He, Zhiguo;Zhuo, Yuting;Li, Shuzhen;Yang, Wenjing;Hu, Liang;Zhong, Hui published 《Rubidium chloride modulated the fecal microbiota community in mice》. 《BMC Microbiology》published the findings. The article contains the following contents:
The microbiota plays an important role in host health. Although rubidium (Rb) has been used to study its effects on depression and cancers, the interaction between microbial commensals and Rb is still unexplored. To gain the knowledge of the relationship between Rb and microbes, 51 mice receiving RbCl-based treatment and 13 untreated mice were evaluated for their characteristics and bacterial microbiome changes. The 16S rRNA gene sequencing of fecal microbiota showed that RbCl generally maintained fecal microbial community diversity, while the shifts in fecal microbial composition were apparent after RbCl exposure. RbCl significantly enhanced the abundances of Rikenellaceae, Alistipes, Clostridium XlVa and sulfate-reducing bacteria including Deltaproteobacteria, Desulfovibrionales, Desulfovibrionaceae and Desulfovibrio, but significantly inhibited the abundances of Tenericutes, Mollicutes, Anaeroplasmatales, Anaeroplasmataceae and Anaeroplasma lineages. With regarding to the archaea, we only observed two less richness archaea Sulfolobus and Acidiplasma at the genus level. Changes of fecal microbes may in part contribute to the anticancer or anti-depressant effects of RbCl. These findings further validate that the microbiome could be a target for therapeutic intervention.Rubidiumchloride (cas: 7791-11-9) were involved in the experimental procedure.
Rubidium chloride(cas: 7791-11-9) can increases dopamine and norepinephrine levels, and useful for anergic and apathetic depressives.SDS of cas: 7791-11-9 Pharmaceutical compositions have been used as antidepressants in Europe. It is employed in biochemistry to induce cells to take up DNA.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics