Chlorinated organic compounds are found in nearly every class of biomolecules. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Application In Synthesis of 104-86-9.
Chen, Kang;Lv, Shan;Lai, Ruizhi;Yang, Zhongzhen;Hai, Li;Nie, Ruifang;Wu, Yong research published 《 Cobalt-Mediated Decarboxylative/Desilylative C-H Activation/Annulation Reaction: An Efficient Approach to Natural Alkaloids and New Structural Analogues》, the research content is summarized as follows. A Co(II)-mediated decarboxylative/desilylative C-H activation/annulation reaction for the efficient synthesis of 3-arylisoquinolines has been developed [e.g., N-benzylpicolinamide + phenylpropiolic acid → 3-phenylisoquinoline (86%) in presence of Co(OAc)2 as catalyst, KPF6 as additive and PEG-400 as solvent; an 80% yield was obtained using 1-phenyl-2-(trimethylsilyl)acetylene instead, under the same optimized conditions.]. Using alkynyl carboxylic acid and alkynyl silane as terminal alkyne precursors provides straightforward routes for the synthesis of natural alkaloids and novel structural analogs.
Application In Synthesis of 104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics