Kubo, Hironori;Matsui, Kaori;Saitoh, Tsuyoshi;Nishiyama, Shigeru published 《Synthesis and assignment of the absolute stereochemistry of (+)-hemifistularin 3》 in 2014. The article was appeared in 《Tetrahedron》. They have made some progress in their research.Computed Properties of C10H13ClO3 The article mentions the following:
The first total synthesis of the marine natural product (+)-hemifistularin 3, I, in enantiomerically pure form was accomplished by using the amide forming reaction of (+)-spiroisoxazoline ester with the (+)-octopamine derivative II. The stereodivergent strategy employed in this effort enabled the assignment of the absolute configurations at the three stereogenic centers in (+)-hemifistularin 3.(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) were involved in the experimental procedure.
(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Computed Properties of C10H13ClO3) is used as a resolving agent for alcohols as the diastereomeric esters by crystallization or chromatography and as a chiral derivatization reagent for determination of enantiomeric excess of alcohols and amines.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics