Zinser, Caroline M.; Warren, Katie G.; Meadows, Rebecca E.; Nahra, Fady; Al-Majid, Abdullah M.; Barakat, Assem; Islam, Mohammad S.; Nolan, Steven P.; Cazin, Catherine S. J. published the artcile< Towards environmentally friendlier Suzuki-Miyaura reactions with precursors of Pd-NHC (NHC = N-heterocyclic carbene) complexes>, Synthetic Route of 1435-43-4, the main research area is palladium NHC complex preparation catalyst green Suzuki Miyaura; green Suzuki Miyaura aryl halide boronic palladium NHC catalyst.
The preparation of [NHC·H][Pd(η3-R-allyl)Cl2] complexes is disclosed and represents a facile, atom-economical, environmentally friendly and rapid synthesis. These palladates are immediate synthetic precursors to the well-known [Pd(NHC)(η3-R-allyl)Cl] complexes. Their activation leading to catalytically relevant species has been studied in the Suzuki-Miyaura reaction. The need for an activation step prior to the catalysis was examined The reaction scope showcases its ease and breadth in terms of functional group tolerance. Electron-donating and electron-withdrawing aryl chlorides and bromides were coupled effectively as well as heteroatom-containing and sterically hindered aryl halides. The catalytic reaction was conducted in ethanol with a weak and inexpensive inorganic base.
Green Chemistry published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 1435-43-4 belongs to class chlorides-buliding-blocks, and the molecular formula is C6H3ClF2, Synthetic Route of 1435-43-4.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics