Thirupataiah, B.; Reddy, Gangireddy Sujeevan; Mounika, Guntipally; Kumar, Jetta Sandeep; Hossain, Kazi Amirul; Mudgal, Jayesh; Mathew, Jessy E.; Shenoy, Gautham G.; Rajadurai, Marina; Parsa, Kishore V. L.; Pal, Manojit published an article in 2021. The article was titled 《Pd-catalysed general access to 7-membered N/O-heterocyclic compounds as potential agents against inflammation》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Formula: C4H3ClO2S2 The information in the text is summarized as follows:
A Pd-catalyzed regioselective synthesis of 4,5-disubstituted 7-membered N/O-heterocycles was achieved via the 7-endo-dig cyclization followed by C-C bond formation of 2-(1-alkynyl)phenylacetamide. The ligand/additive free cascade reaction proceeded in the presence of PdCl2 in aqueous MeCN when the sep. and individual use of Me vinyl ketone and allyl bromide generally afforded an O- and N-heterocycle, resp. The pharmacol. assay was performed to identify the first example of a 1H-benzo[d]azepin-2(3H)-one based novel inhibitor of PDE4B. The results came from multiple reactions, including the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Formula: C4H3ClO2S2)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Formula: C4H3ClO2S2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics