Category: 118-69-4

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 118-69-4, name is 2,6-Dichlorotoluene, A new synthetic method of this compound is introduced below., Recommanded Product: 2,6-Dichlorotoluene

The 161g2, 6 – dichloro toluene is added has been alkanes 87 g solvent after dissolving, adding copper sulfide catalyst 2.8 g, stirring, case of illumination, access chlorine, time 5 hours, to maintain the reaction temperature 80 – 120 C, reaction the exhaust gas through the water absorption, after the reaction, the reaction solution chloride washing, alkali cleaning, distillation to remove the solvent after cooling crystallization, filtering to obtain 174.5 g purity 99% of 2, 6 – […], yield 90.3%, .

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Sinopec Corporation; Nan Hua Group Institute; Zhao Fubao; Ma Min; Li Haitao; (4 pag.)CN109721464; (2019); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 118-69-4, name is 2,6-Dichlorotoluene, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 2,6-Dichlorotoluene

This Example demonstrates the preparation of 2,6-dichloro-3,5-dinitrotoluene.To a 1 L 4-neck round bottom flask equipped with external ice cooling, mechanical stirrer, addition funnel, N2 inlet, and thermometer was added 118 g (1.872 mmol) fuming nitric acid (d=1.54). With cooling, 745 g (1863 mmol SO3) 20% oleum was added over a period of 30 minutes while maintaining a temperature below 30 C. The acid solution was cooled to 0-5 C. and 150 g (932 mmol) 2,6-dichlorotoluene was slowly added over 2 h while maintaining a temperature below 20 C. When addition was complete, the ice bath was removed and the reaction mixture was slowly allowed to warm to room temperature. It was then heated from room temperature to 110 C. over a time period of 45 min. After 15 min at 110 C., the reaction mixture was allowed to cool to room temperature and then cooled to 5 C. It was then filtered through a glass flitted funnel and washed with 250 mL water followed by 250 mL 10% aqueous NH3 solution to yield a pale yellow crystalline wet cake. A small sample was dried in vacuum and analyzed by both H1-NMR and GC and found to be 99.9% pure. The wet cake (219 g) contained about 201.5 g 2,6-dichloro-3,5-dinitrotoluene and 17.5 g water. The net yield of 2,6-dichloro-3,5-dinitrotoluene amounted to about 86%.

According to the analysis of related databases, 118-69-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; E.I. DU PONT DE NEMOURS AND COMPANY; US2010/160675; (2010); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Adding a certain compound to certain chemical reactions, such as: 118-69-4, name is 2,6-Dichlorotoluene, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 118-69-4, Application In Synthesis of 2,6-Dichlorotoluene

5 g of the following catalyst particles, as described in examples 3 and 4, were loaded in the reactor along with the diluent corundum particles (1: 1 by weight) and tested the influence of addition of ethyl bromide (2 % VN) in presence and absence of water vapour. The reaction was performed under the following conditions. A reaction temperature of 350 to [400C] was used. The mole ratio 2,6-DCT : H20 : NH3: air: N2 was 1: 15: 3-4: 21: 0-29. Molar concentration of 2,6-DCT is 1.4 to 3.8 %.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2,6-Dichlorotoluene, and friends who are interested can also refer to it.

Reference:
Patent; TESSENDERLO CHEMIE S.A.; WO2003/101939; (2003); A2;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Related Products of 118-69-4, The chemical industry reduces the impact on the environment during synthesis 118-69-4, name is 2,6-Dichlorotoluene, I believe this compound will play a more active role in future production and life.

5 g of catalyst, as described in examples 3 and 4, was loaded in the reactor along with the diluent corundum particles (1: 1 by weight) and the reaction was performed under the following conditions. A reaction temperature of 350 to [400C] was used, and the GHSV comprised between 650-750 [H-1.] The contact time consisted of 4.8 to 5.5 seconds. The mole ratio of 2,6-DCT : H20 : NH3: air: N2 was 1: 15: 3-4: 21, the molar concentration of 2,6- DCT was 2.4 % and the ratio of [0/NH3] was 1. [1 %.] 5 g [VPCRO/TI02] (anatase) catalyst, as described in examples 3 and 4, was loaded in the reactor together with the diluent corundum particles (1: 1 by weight) and tested the influence of water vapour in the feed gas on the catalytic performance of the catalyst. The reaction was performed under the following reaction conditions. A reaction temperature of 350 to [400C] was used. The mole ratio of 2,6-DCT : NH3: air was 1: 4: 21, the molar concentration of 2,6-DCT was 2.1 to 3.8 %, and the ratio of [0/NHS] was 1. [1 %.]

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,6-Dichlorotoluene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; TESSENDERLO CHEMIE S.A.; WO2003/101939; (2003); A2;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Electric Literature of 118-69-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 118-69-4 name is 2,6-Dichlorotoluene, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

235.0 g (3.0 mol) of acetyl chloride were added dropwise with stirring at 100 C. in the course of 2 hours to a solution of 502.0 g (3.12 mol) of 2,6-dichlorotoluene and 408.0 g (3.06 mol) of aluminum trichloride. After the mixture had been stirred for 2 hours at 100-105 C. it was cooled, and the reaction mixture was poured onto 3 l of ice and 1 l of water. The solid which had precipitated during this process was filtered off with suction and washed to neutrality with 800 ml of water. After drying at 40 C., 500.0 g of 2,4-dichloro-3-methylacetophenone were obtained as crude product, which were subsequently distilled under a high vacuum. (Boiling point: 121-128 C. (4 mbar))

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2,6-Dichlorotoluene, and friends who are interested can also refer to it.

Reference:
Patent; BASF Aktiengesellschaft; US6028035; (2000); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Related Products of 118-69-4,Some common heterocyclic compound, 118-69-4, name is 2,6-Dichlorotoluene, molecular formula is C7H6Cl2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

5 g of the following catalyst particles, as described in examples 3 and 4, were loaded in the reactor along with the diluent corundum particles (1: 1 by weight) and tested the influence of addition of ethyl bromide (2 % VN) in presence and absence of water vapour. The reaction was performed under the following conditions. A reaction temperature of 350 to [400C] was used. The mole ratio 2,6-DCT : H20 : NH3: air: N2 was 1: 15: 3-4: 21: 0-29. Molar concentration of 2,6-DCT is 1.4 to 3.8 %.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2,6-Dichlorotoluene, its application will become more common.

Reference:
Patent; TESSENDERLO CHEMIE S.A.; WO2003/101939; (2003); A2;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 118-69-4, name is 2,6-Dichlorotoluene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Formula: C7H6Cl2

Sub-step 1.1: In a 3000mL three-necked flask, add solid sodium methoxide 450g and dimethyl sulfoxide 700g, stir and heat up to 180 , start dropwise addition of 2,6-dichlorotoluene 1000g, after 4h dropwise addition, keep the reaction 2 hours, transfer to a distillation flask, distill dimethyl sulfoxide under reduced pressure through a rectification column (applied in the next batch), and distill under reduced pressure for 5 hours at a temperature of 130 C and a pressure of -0.095MPa.Distilled substrate.Substep 1.2: Transfer the distillation substrate to a three-necked flask, add 80g of dimethyl sulfate dropwise at 80 C, complete the dropwise addition within 2h, hold the reaction for 1.5 hours, add 1500g of water, and after washing, transfer the oil layer to the distillation flask. Distillation under reduced pressure for 8 hours at a temperature of 120 C and a pressure of -0.095MPa,906.1g of 2-methyl-3-chloroanisole was obtained.

The synthetic route of 118-69-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Xi’an Zhengyang Jiahe Chemical Technology Co., Ltd.; Guo Xiangxiang; (8 pag.)CN111018693; (2020); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Adding a certain compound to certain chemical reactions, such as: 118-69-4, name is 2,6-Dichlorotoluene, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 118-69-4, Safety of 2,6-Dichlorotoluene

To a 25 mL reaction flask was added 1,3-diphenylpropanedione iron (0.025 mmol) in turn,Ferrous phthalocyanine (0.0025 mmol),Triethoxy carveda (1.5 mmol)Sodium persulfate (0.75 mmol),(L · 25 mmol), acetone (lmL), water (lmL), and the reaction mixture was reacted at 80 C for 17 h. The reaction was terminated with the addition of aqueous ammonia (2 mL) to remove the polymethylhydrogensiloxane, 10 mL of saturated brine was added and extracted with ether (10 mL X3). The organic phases were combined and the solvent was evaporated under reduced pressure.To 60% yield.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.

Reference:
Patent; Nanjing Normal University; Han Wei; Zhao Hongyuan; (14 pag.)CN107216242; (2017); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Adding a certain compound to certain chemical reactions, such as: 118-69-4, name is 2,6-Dichlorotoluene, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 118-69-4, Computed Properties of C7H6Cl2

EXAMPLE 1-1 Preparation of 2,4-dichloro-3-methylbromobenzene To a solution of 48.8 g (0.3 mol) of 2,6-dichlorotoluene in 60 ml of carbon tetrachloride, 0.7 g of iron powder and 0.1 g of iodine were added. Then, 52.8 g (0.33 mol) of bromine was dropwise added thereto at room temperature while maintaining the reaction temperature at a level of from 22 to 25 C. After completion of the dropwise addition, the reaction was continued at the same temperature until generation of hydrogen bromide ceased. After the reaction, the reaction solution was added to 300 ml of ice water and extracted with 300 ml of 1,2-dichloroethane. The organic layer was separated and washed sequentially with water, a saturated sodium hydrogen sulfite aqueous solution, water and a saturated sodium chloride aqueous solution. Then, the solvent was distilled off under reduced pressure to obtain 71.9 g (yield: 99.5%) of desired 2,4-dichloro-3-methylbromobenzene. Melting point: 32-33 C.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2,6-Dichlorotoluene, and friends who are interested can also refer to it.

Reference:
Patent; Nissan Chemical Industries Ltd.; US4942246; (1990); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 118-69-4, name is 2,6-Dichlorotoluene, A new synthetic method of this compound is introduced below., Application In Synthesis of 2,6-Dichlorotoluene

EXAMPLE 1-1 Preparation of 2,4-dichloro-3-methylbromobenzene To a solution of 48.8 g (0.3 mol) of 2,6-dichlorotoluene in 60 ml of carbon tetrachloride, 0.7 g of iron powder and 0.1 g of iodine were added. Then, 52.8 g (0.33 mol) of bromine was dropwise added thereto at room temperature while maintaining the reaction temperature at a level of from 22 to 25 C. After completion of the dropwise addition, the reaction was continued at the same temperature until generation of hydrogen bromide ceased. After the reaction, the reaction solution was added to 300 ml of ice water and extracted with 300 ml of 1,2-dichloroethane. The organic layer was separated and washed sequentially with water, a saturated sodium hydrogen sulfite aqueous solution, water and a saturated sodium chloride aqueous solution. Then, the solvent was distilled off under reduced pressure to obtain 71.9 g (yield: 99.5%) of desired 2,4-dichloro-3-methylbromobenzene. Melting point: 32-33 C.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Nissan Chemical Industries Ltd.; US4942246; (1990); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics