Category: 1186603-47-3

A New Rhodium/Copper-Cocatalyzed C-H Oxidation for the Preparation of Isoquinolin-1-ones was written by Zhou, Zeng-Le;Liu, Yi-Lin;Song, Jian-Lan;Deng, Chen-Liang. And the article was included in Synthesis in 2016.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

A new and efficient rhodium/copper-cocatalyzed C-H oxidation reaction of isoquinolinium N-amides was developed. In the presence of rhodium(II) acetate dimer, copper(II) chloride, a ligand and sodium tert-butoxide, a variety of isoquinolin-1-ones were prepared in moderate to good yields via ortho C-H oxidation This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Category: chlorides-buliding-blocks).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Generation of Diverse 2H-Isoindol-1-ylphosphonates via Three-Component Reaction of 2-Alkynylbenzaldehyde, Aniline, and Phosphite was written by Yu, Xingxin;Ding, Qiuping;Wu, Jie. And the article was included in Journal of Combinatorial Chemistry in 2010.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

Diverse 2H-isoindol-1-ylphosphonates as potential HCT-<116â‰?inhibitors are easily generated via a FeCl₃ and PdCl₂ cocatalyzed three-component reaction of 2-alkynylbenzaldehyde, aniline, and phosphite. The focused small library is constructed based on parallel diversity-oriented synthesis. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Category: chlorides-buliding-blocks).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Silver-catalyzed tandem nucleophilic addition/cycloisomerization of ortho-alkynylbenzaldehydes: Regioselective synthesis of functionalized 1H-isochromene derivatives was written by Li, Fang-Hui;Li, Jian;Wang, Shun-Yi;Ji, Shun-Jun. And the article was included in Tetrahedron in 2017.Electric Literature of C15H9ClO The following contents are mentioned in the article:

An efficient silver-catalyzed domino cycloisomerization reaction for regioselective assembly of 1H-isochromene derivatives from o-alkynylaryl aldehydes with enaminones as the external nucleophiles is developed. This protocol affords isochromene derivatives in moderate to good yields under simple and mild reaction conditions. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Electric Literature of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Electric Literature of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Facile Assembly of H-Pyrazolo[5,1-a]isoquinolines via Silver Triflate-Catalyzed One-Pot Tandem Reaction of 2-Alkynyl- benzaldehyde, Sulfonohydrazide, and Ketone or Aldehyde was written by Yu, Xingxin;Ye, Shengqing;Wu, Jie. And the article was included in Advanced Synthesis & Catalysis in 2010.Computed Properties of C15H9ClO The following contents are mentioned in the article:

A novel and efficient route for the generation of H-pyrazolo[5,1-a]isoquinolines via silver triflate-catalyzed one-pot tandem reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and ketone or aldehyde is described. This reaction proceeds with good functional group tolerance under mild conditions with high efficiency and excellent selectivity. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Computed Properties of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Bronsted acid-promoted dimerization of o-alkynylbenzaldehydes: a one-step synthesis of functionalized Kagan’s ether analogues was written by Zhang, Hao;Cui, Wei-Chen;Hu, Zhi-Long;Yu, Shu-Yan;Wang, Shaozhong;Yao, Zhu-Jun. And the article was included in RSC Advances in 2012.Safety of 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

The Bronsted acid-promoted dimerization of o-alkynylbenzaldehydes has been discovered and studied in the presence of 45% aqueous HBF₄ in acetic acid. The developed cascade methodol. provides a convenient one-step synthesis of sym. 2,3,6,7-dibenzo-9-oxabicyclo[3.3.1]nona-2,6-diene (Kagan’s ether) analogs bearing various functionalities. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Safety of 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Safety of 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Merging Gold and Organocatalysis: A Facile Asymmetric Synthesis of Annulated Pyrroles was written by Hack, Daniel;Loh, Charles C. J.;Hartmann, Jan M.;Raabe, Gerhard;Enders, Dieter. And the article was included in Chemistry – A European Journal in 2014.Reference of 1186603-47-3 The following contents are mentioned in the article:

The combination of cinchona-alkaloid-derived primary amine and Au^I-phosphine catalysts allowed the selective C-H functionalization of two adjacent carbon atoms of pyrroles under mild reaction conditions. This sequential dual activation provides seven-membered-ring-annulated pyrrole derivatives in excellent yields and enantioselectivities. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Reference of 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Reference of 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An expeditious approach to 1-(isoquinolin-1-yl)guanidines via a three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, with carbodiimide was written by Wang, Huanhuan;Ye, Shengqing;Jin, Hanpeng;Liu, Jianping;Wu, Jie. And the article was included in Tetrahedron in 2011.Application In Synthesis of 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

A small library of 1-(isoquinolin-1-yl)guanidine is constructed efficiently via a silver triflate-catalyzed three-component reaction of 2-alkynylbenzaldehydes, tosyl hydrazine, and carbodiimides. The preliminary biol. screens of these isoquinoline library members have been evaluated, which show promising results for PTP1B inhibition and HCT-116 inhibition. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Application In Synthesis of 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Application In Synthesis of 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Silver Triflate Catalyzed Synthesis of Isoquinolino[2,1-a]quinazolino[3,2-c]quinazoline Derivatives via Alkyne Hydroamination was written by Pan, Wan-Chen;Zhang, Mei-Mei;Liu, Jian-Quan;Wang, Xiang-Shan. And the article was included in Synthesis in 2019.Recommanded Product: 1186603-47-3 The following contents are mentioned in the article:

Using 2-(2-aminophenyl)quinazolin-4(3H)-one and 2-(2-phenylethynyl)benzaldehyde as the reactants, silver triflate (AgOTf) was proved to be an efficient catalyst to promote not only quinazoline cyclization, but also the intramol. hydroamination of alkyne for the synthesis of 6-aryl-17H,18aH-isoquinolino[2,1-a]quinazolino[3,2-c]quinazolin-17-one derivatives in high yields. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Recommanded Product: 1186603-47-3).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Recommanded Product: 1186603-47-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

CuI/I₂-promoted electrophilic tandem cyclization of 2-ethynylbenzaldehydes with ortho-benzenediamines: Synthesis of Iodoisoquinoline-Fused Benzimidazoles was written by Ouyang, Huang-Che;Tang, Ri-Yuan;Zhong, Ping;Zhang, Xing-Guo;Li, Jin-Heng. And the article was included in Journal of Organic Chemistry in 2011.Formula: C15H9ClO The following contents are mentioned in the article:

An efficient tandem route to the synthesis of iodo isoquinoline-fused benzimidazole derivatives, e.g., I including an iodocyclization strategy has been developed. In the presence of CuI, a variety of 2-ethynylbenzaldehydes underwent the tandem reaction with benzenediamines and iodine to afford the corresponding iodo isoquinoline-fused benzimidazoles in moderate to good yields. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Formula: C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Formula: C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Iodine-catalyzed synthesis of 5-benzoyl-8H-phthalazino[1,2-b]quinazolin-8-one derivatives via a domino reaction involving a benzyl automatic oxidation by oxygen was written by Liu, Jian-Quan;Feng, Bin-Bin;Wang, Xiang-Shan. And the article was included in Tetrahedron in 2018.Quality Control of 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

A one-pot procedure for the synthesis of 5-benzoyl-8H-phthalazino[1,2-b]quinazolin-8-ones was achieved by an iodine-catalyzed reaction of 2-aminobenzohydrazides and 2-alkynylbenzaldehydes in good yields. The salient feature of this strategy is a domino type process including a condensation, addition, hydroamination, and a noteworthy benzyl automatic oxidation by oxygen under metal-catalyst-free conditions. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Quality Control of 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Quality Control of 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics