Category: 14862-52-3

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 14862-52-3, name is 3,5-Dibromochlorobenzene, A new synthetic method of this compound is introduced below., HPLC of Formula: C6H3Br2Cl

1-chloro-3,5-dibromobenzene (5.40 g, 20 mmol) and 3-pyridine boronic acid (5.17 g, 42 mmol) were added to a 100 mL three neck round bottom flask. To this flask, dioxane (80 mL) and aqueous K2CO3 (2 N, 40 mL) were added. The mixture was stirred and degassed with a steam of argon for 30 minutes. Then under argon atmosphere, 200 mg (0.16 mmol) Pd(PPh3)4 was added. The mixture was brought to 100 C. and stirred overnight. The next day, solvent was removed by roto-evaporation and residue was suspended into an equal amount of water (50 mL) and CH2Cl2 (50 mL). The organic layer was separated from aqueous layer and washed with brine (50 mL×3). After drying over Na2SO4, and removal of drying agent, 5.33 g transparent liquid 3,3′-(5-chloro-1,3-phenylene)dipyridine (100%, Compound L) was obtained. 1H NMR (400 MHz, CDCl3) 8.91 (s, 2H), 8.69 (d, 2H), 7.95 (d, 2H), 7.66 (s, 1H), 7.63 (s, 2H), 7.50-7.44 (m, 2H).

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; General Electric Company; US2010/331547; (2010); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Adding a certain compound to certain chemical reactions, such as: 14862-52-3, name is 3,5-Dibromochlorobenzene, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 14862-52-3, Safety of 3,5-Dibromochlorobenzene

3-cyanophenyl boronic acid (25.0 g, 0.17 mol) and 1,3-dibromo-5-chlorobenzene (23.0 g, 0.08 mol) Dissolved in 290 mL of tetrahydrofuran, 1.5 M aqueous potassium carbonate solution (90 mL) was added,Tetrakis- (triphenylphosphine) palladium (3.94 g, 0.34 mmol) was added thereto, followed by heating with stirring for 13 hours.The temperature was lowered to room temperature, the water layer was separated off, dried over anhydrous magnesium sulfate and concentrated under reduced pressureRecrystallization was performed using chloroform and ethanolWas dried to prepare the intermediate n (44.7 g, yield 83%).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3,5-Dibromochlorobenzene, and friends who are interested can also refer to it.

Reference:
Patent; LG Chem, Ltd.; Lee Jeong-ha; Moon Jeong-uk; Jeong Min-u; Lee Dong-hun; Chae Mi-yeong; (49 pag.)KR2018/32517; (2018); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 14862-52-3, name is 3,5-Dibromochlorobenzene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Safety of 3,5-Dibromochlorobenzene

Vapor phase chlorination step: A reactor equipped with a lateral reaction tube (diameter of 4 cm, length of 50 cm), a vaporizer and a preheating tube which are capabe of outward temperature control, was used and 1 mol of chlorine gas preheated at 300 C. was fed into the reaction tube and a solution of 1 mol of 1-chloro-3,5-dibromobenzene in 5 mol of carbon tetrachloride was preheated at 300 C. to vaporize it and the vapor was fed into the reaction tube during 50 minutes to react them at 340 C. The residence time of the reaction mixture was about 50 seconds. The discharged gas from the reaction tube was fed into an alkaline aqueous solution of sodium thiosulfate to collect the reaction product. The phase separation was carried out at room temperature and carbon tetrachloride was distilled off to obtain oily product. The oily product was distilled to obtain 165 g. of 1,3,5-trichlorobenzene in yield of 91%.

The synthetic route of 14862-52-3 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Ishihara Sangyo Kaisha Ltd.; US4368340; (1983); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Application of 14862-52-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 14862-52-3, name is 3,5-Dibromochlorobenzene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

To a stirred solution of 1,3-dibromo-5-chlorobenzene (800 mg, 2.96 mmol) and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (600 mg, 2.96 mmol) in 1,4-dioaxane (15 mL) K2CO3 (1.2 g, 8.80 mmol) was added and the mixture was degassed with argon for 20 minutes. Pd (PPh3)4 (102 mg, 0.08 mmol) was added to reaction mixture and degassed for another 20 minutes. The reaction mixture was refluxed under stirring for 8 hours and then filtered through celite pad. The filtrate was concentrated and the residue was purified by column chromatography on silica (100-200 mesh) eluting with 15% ethyl acetate in petroleum ether to afford the title compound as white solid (400 mg, 50 %). 1H NMR: (300 MHz, CDCl3) delta 8.70 (dd, J = 4.5, 1.5 Hz, 2H), 7.65-7.64 (m, 1H), 7.59-7.58 (m, 1H), 7.54-7.53 (m, 1H), 7.45 (dd, J = 4.2, 1.5 Hz, 2H); ESIMS: m/z = 268.0 [(M+H)+].

The synthetic route of 3,5-Dibromochlorobenzene has been constantly updated, and we look forward to future research findings.

Reference:
Article; Blass, Benjamin E.; Iyer, Pravin; Abou-Gharbia, Magid; Childers, Wayne E.; Gordon, John C.; Ramanjulu, Mercy; Morton, George; Arumugam, Premkumar; Boruwa, Joshodeep; Ellingboe, John; Mitra, Sayan; Reddy Nimmareddy, Rajashekar; Paliwal, Shalini; Rajasekhar, Jamallamudi; Shivakumar, Savithiri; Srivastava, Pratima; Tangirala, Raghuram S.; Venkataramanaiah, Konda; Bobbala, Ramreddy; Yanamandra, Mahesh; Krishnakanth Reddy; Bioorganic and Medicinal Chemistry Letters; vol. 28; 13; (2018); p. 2270 – 2274;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Related Products of 14862-52-3, The chemical industry reduces the impact on the environment during synthesis 14862-52-3, name is 3,5-Dibromochlorobenzene, I believe this compound will play a more active role in future production and life.

A solution of 1,3-dibromo-5-chlorobenzene (10 mmol, 3.2 g)Diphenylamine (40 mmol, 6.7 g) was added to a 100 mL three-necked flask,A cuprous iodide (4 mmol, 0.8 g) was added under nitrogen,Potassium carbonate (40 mmol, 2.8 g),Phenanthroline (4 mmol, 0.8 g),50 mL of DMF,The reaction was carried out at 155 C for 3 days,The resulting reaction product is subjected to extraction,The extracted organic phase was evaporated to dryness with ethanol,And then recrystallized from ethyl acetate and petroleum ether to give 3.57 g of intermediate A-4,

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,5-Dibromochlorobenzene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Jilin Aolai De Optoelectronic Materials Co., Ltd.; Gao, Chunji; Cui, Dunzhu; Sun, Yi; Zhang, Chengcheng; (52 pag.)CN104892434; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Electric Literature of 14862-52-3, The chemical industry reduces the impact on the environment during synthesis 14862-52-3, name is 3,5-Dibromochlorobenzene, I believe this compound will play a more active role in future production and life.

3,5-dibromochlorobenzene (2.7 g, 10 mmol)9-phenylcarbazole-3-boronic acid (6.0 g, 21 mmol)Sodium carbonate (10.2 g, 96 mmol),Pd2 (dba) 3 (0.4 g, 0.4 mmol), toluene,Ethanol, water 50ml in turn added to the reaction bottle,The reaction was refluxed under nitrogen for 10 hours, cooled to room temperature,The aqueous layer was extracted with ethyl acetate,The organic layers were combined, washed with saturated brine and water, respectively,The organic layer was dried over magnesium sulfate, filtered,Filtrate spin dry, over silicone column,4.4 g of product was obtained, HPLC purity 99.2%.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,5-Dibromochlorobenzene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; CECEP Wanrun Co., Ltd.; Yu Kaichao; Zhang Zhaochao; Wang Lichun; (35 pag.)CN107056806; (2017); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reference of 14862-52-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 14862-52-3, name is 3,5-Dibromochlorobenzene, This compound has unique chemical properties. The synthetic route is as follows.

Toluene (200 ml) and water (50 ml)Of (9,9-dimethyl-9H-fluorene -2-yl) boronic acid (5.0 g, 21.0 mmol), 1,3-dibromo-5-chlorobenzene (14.19 g, 52.5 mmol), Pd (PPh3 ) it is refluxed in a solution of 4 (0.49 g, 0.42 mmol), and K2CO3 (5.80 g, 42.0 mmol) under nitrogen for 18 hours. After cooling to room temperature (~ 22 ), isolating the organic layer it was distilled off excess 1,3-dibromo-5-chlorobenzene. The residue as eluent heptane / DCM (9/1, v / v) for purification by column chromatography on silica gel, and as a colorless crystalline solid 2- (3-bromo-5-chlorophenyl) -9, 9-dimethyl -9H- FluoreneTo give a (6.2 g, 77%).

The chemical industry reduces the impact on the environment during synthesis 3,5-Dibromochlorobenzene. I believe this compound will play a more active role in future production and life.

Reference:
Patent; Universal Display Corporation; Cheng, Licang; Rayekh, Suman; Vaudreuil, Pierre Ruik-T; Elshennawy, Zaineb; Kottas, Greg; Diatkine, Alexei Borysovych; Joseph, Scott; Adamowicz, Vadim; Xia, Chuanjun; Wang, Ting Chiu; Jage, Walter; (109 pag.)KR2016/6633; (2016); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 14862-52-3, Name is 3,5-Dibromochlorobenzene, SMILES is C1=C(C=C(Br)C=C1Br)Cl, in an article , author is Wang, Qiongjie, once mentioned of 14862-52-3, Name: 3,5-Dibromochlorobenzene.

Although more attention has been paid to plastic pollution in marine ecosystems, research on the influence of plastic in freshwater ecosystems remains limited. To help fill this information gap, this article represents an investigation of the effects of virgin polyvinyl chloride (v-PVC) microparticles (MPs) and UV-aged polyvinyl chloride (a-PVC) MPs on the growth and chlorophyll content of the freshwater algae, Chlamydomonas reinhardtii (C. reinhardtii) at different periods (0, 24, 48, 72 and 96 h). The results suggest that both virgin and aged PVC MPs have negative effects on the growth of C. reinhardtii in the range 01 10 mg/L to 200 mg/L, which leads to the reduction of chlorophyll-a level in the cells. Furthermore, a-PVC MPs were more toxic than v-PVC MPs, as shown by the a-PVC MPs lower EC50 values after 96 h (63.66 mg/L for a-PVC MPs and 104.93 mg/L. for v-PVC MPs). The inhibition effect of both kinds of PVC was also testified by the enhancement of enzymatic activity of superoxide dismutase (SOD) and malondialdehyde (MDA) in algae. Meanwhile, a-PVC MPs obviously had a higher toxicity than v-PVC MPs. The aging process that affected the surface characteristics of a-PVC was identified using Fourier transform infrared (FUR) and Zetasizer. The carbonyl groups formed on the surface and the increased zeta potential of the a-PVC MPs affected the interaction between the microplastics and the algae, which increased the toxicity of aged microplastics. The research results presented here provide more evidence of the risks microplastics bring into the freshwater ecosystem. (C) 2020 Elsevier B.V. All rights reserved.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 14862-52-3, you can contact me at any time and look forward to more communication. Name: 3,5-Dibromochlorobenzene.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Synthetic Route of 14862-52-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 14862-52-3, Name is 3,5-Dibromochlorobenzene, SMILES is C1=C(C=C(Br)C=C1Br)Cl, belongs to chlorides-buliding-blocks compound. In a article, author is Wang, Qiangming, introduce new discover of the category.

A sensitive and selective amperometric determination method for isoniazid (INZ), an anti-tuberculosis drug, was studied by cyclic voltammetry and chronoamperometry, using carbon doped vanadium trioxide @ Prussian blue modified graphite felt electrodes (V2O3-C@PB/GF). V2O3-C was synthesized by a solvothermal technique and fixed on GF; then PB was generated on the so-obtained V2O3-C/GF. The morphology and structure of the composite electrode were characterized via X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FT-IR) spectroscopy and ultraviolet-visible (UV-vis) spectroscopy. After optimization of the parameters influencing the formation of V2O3-C@PB/GF, the composite electrode showed efficient electrocatalytic performance for isoniazid detection in 0.5 M potassium chloride (KC1) solution. A wide linear concentration range (2.5 x10(-)(9)-1.1 x10(-3) M), a good sensitivity (1.378 AIM, 0.561 ABM) and a low detection limit (0.83 nM) were obtained. Furthermore, long-term stability and fabrication reproducibility of the electrochemical device have been investigated, as well as its robustness to interferent species. Finally, the practical applicability of the proposed sensor was assessed by detecting INZ in commercial tablets, bovine serum albumin and human urine samples: recovery values varied from 96.8% to 105.2%, indicating an excellent analytical performance for INZ qualification. (C) 2020 Elsevier B.V. All rights reserved.

Synthetic Route of 14862-52-3, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 14862-52-3.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Synthetic Route of 14862-52-3, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 14862-52-3, Name is 3,5-Dibromochlorobenzene, SMILES is C1=C(C=C(Br)C=C1Br)Cl, belongs to chlorides-buliding-blocks compound. In a article, author is Feng, Jina, introduce new discover of the category.

Cement carbonation, one of the main causes of the reinforced concrete corrosion, is also inevitable in the geological environment of carbon sequestration, possibly destroying the integrity of well/cement system. To evaluate the corrosion risk of casing pipe in a geothermal well environment, the corrosion behavior of P110 steel was investigated in carbonated cement pore solutions under carbon dioxide supercritical conditions. It was found that a dense FeCO3 layer was generally formed and it could effectively prevent the steel from corrosion. However, above the threshold concentrations of chloride ion and dissolved oxygen, localized corrosion protrusions could be observed, which might continuously grow larger and higher until its outer shell ruptured during the exposure of the steel substrate in the simulated environment. The expansive growth of the protrusion could be attributed to the active dissolution accelerated by chloride ion at the bottom and the cooperative formation of iron oxide and carbonate in the core region. Such a localized corrosion damage could occur at the casing/cement interface in practice and may become a fatal threat to casing pipes for carbon sequestration in the oil/gas industry. (C) 2020 Elsevier Ltd. All rights reserved.

Synthetic Route of 14862-52-3, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 14862-52-3.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics