Category: 16629-19-9

Gillaizeau-Simonian, Nicolas; Barde, Etienne; Guerinot, Amandine; Cossy, Janine published their research in Chemistry – A European Journal in 2021. The article was titled 《Cobalt-Catalyzed 1,4-Aryl Migration/Desulfonylation Cascade: Synthesis of α-Aryl Amides》.Product Details of 16629-19-9 The article contains the following contents:

A cobalt-catalyzed 1,4-aryl migration/disulfonylation cascade applied to α-bromo N-sulfonyl amides was developed. The reaction was highly chemoselective, allowed the preparation of α-aryl amides possessed a variety of functional groups. The method was used as the key step to synthesize an alkaloid, (±)-deoxyeseroline. Mechanistic investigations suggested a radical process. In the part of experimental materials, we found many familiar compounds, such as Thiophene-2-sulfonyl chloride(cas: 16629-19-9Product Details of 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Product Details of 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Xie, Dandan; Yang, Zaiping; Hu, Xin; Wen, Yin published an article in 2022. The article was titled 《Synthesis, antibacterial and insecticidal activities of novel capsaicin derivatives containing a sulfonic acid esters moiety》, and you may find the article in Frontiers in Chemistry (Lausanne, Switzerland).Application of 16629-19-9 The information in the text is summarized as follows:

In order to develop an efficient and broad-spectrum bactericide, a series of novel capsaicin derivatives containing a sulfonic acid esters moiety was synthesized. The structure of these compounds were confirmed by NMR spectroscopy (NMR) and high-resolution mass spectrum (HRMS). The results of the bioactivities revealed that some target compounds exhibited remarkable antibacterial activity. Compound 3b exhibited the highest activities against Pseudomonas syringae pv. actinidiae (Psa), Xanthomonas oryzae pv. oryzae (Xoo), and Xanthomonas axonopodis pv. citri (Xac), and the values were 86, 54, and 92% at 50 μg/mL, resp., which were higher than were for thiodiazole copper (87, 34, and 77%) and bismerthiazol (87, 37 and 75%). Although some compounds also showed certain activity against Spodoptera frugiperda, it was weaker than the pos. controls monosultap and mulfoxaflor. Thus, the bioassay results recommend that these newly designed and synthesized scaffolds should be used as a bactericide lead compound rather than an insecticide lead compound In the part of experimental materials, we found many familiar compounds, such as Thiophene-2-sulfonyl chloride(cas: 16629-19-9Application of 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Application of 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Li, Yuxiu; Li, Xiangqian; Li, Xiaowei; Shi, Dayong published an article in 2021. The article was titled 《Visible-light-promoted E-selective synthesis of α-fluoro-β-arylalkenyl sulfides via the deoxygenation/isomerization process》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Electric Literature of C4H3ClO2S2 The information in the text is summarized as follows:

Regioselective synthesis of α-fluoro-β-arylalkenyl sulfides (E/Z)-Ar(R1)C=C(F)SR (R = 4-ClC6H4, 2-naphthyl, 2-thienyl, etc.; R1 = H, CH3, C6H5; Ar = 4-BrC6H4, 2-naphthyl, quinolin-3-yl, etc.) has been established with gem-difluoroalkenes Ar(R1)C=C(F)2 and sodium sulfinates RS(O)2Na in a transition-metal-free manner. A series of control experiments was executed to demonstrate thiol radicals and anions as the proposed intermediates. Notably, regioselective Z → E isomerization was achieved under green light irradiation in the absence of a photoinitiator. In addition to this study using Thiophene-2-sulfonyl chloride, there are many other studies that have used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Electric Literature of C4H3ClO2S2) was used in this study.

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Electric Literature of C4H3ClO2S2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Iridium-catalyzed C-H amidation of s-tetrazines》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Xiong, Huan; Gu, Yuang; Zhang, Shuning; Lu, Fengping; Ji, Qun; Liu, Lili; Ma, Peixiang; Yang, Guang; Hou, Wei; Xu, Hongtao. Quality Control of Thiophene-2-sulfonyl chloride The article mentions the following:

An efficient, selective and scalable C-H amidation of s-tetrazines under iridium(III) catalysis was reported to affor amido-aryl tetrazines such as I [R1 = H, 3-Br, 4-CF3, etc.; R2 = NHSO2n-Bu, NHSO2Ph, NHTs, etc.; R3 = H, NHSO2Ph, NHTs, etc.]. This reaction featured a broad substrate scope, high functional group tolerance and air and water tolerance. This reaction also showed great potential for the rapid preparation of tri- and tetra-functional building blocks, which could be applied either in bioconjugation or synthesis of DNA-encoded library. In the experimental materials used by the author, we found Thiophene-2-sulfonyl chloride(cas: 16629-19-9Quality Control of Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Quality Control of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Product Details of 16629-19-9In 2022 ,《Visible-light photocatalytic radical addition-translocation-cyclization to construct sulfonyl-containing azacycles》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Liang, Yu-Qing; Xu, Yi-Xin; Cai, Zhong-Jian; Ji, Shun-Jun. The article conveys some information:

Herein, a novel visible-light photocatalytic radical addition-translocation-cyclization (RATC) approach for the efficient synthesis of sulfonyl-containing azacycles is described. The reaction delivers a wide range of monocyclic, bicyclic and polycyclic azacycles by using easily prepared sodium sulfinates and N-homopropargylic amines as starting materials. Instead of the traditionally used toxic tin reagents and thermally hazardous azos in the RATC process, clean, renewable and sustainable visible light combined with a catalytic amount of photosensitizer is used in this process. Moreover, the successful transformation of some drug derivatives further highlights the potential application of this procedure. The results came from multiple reactions, including the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Product Details of 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Product Details of 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis of di(hetero)aryl sulfides by defluorinative sulfenylation of polyfluoroalkyl ketones with sodium sulfinates or arylsulfonyl chlorides》 was written by Chu, Xue-Qiang; Xie, Ting; Wang, Ya-Wen; Li, Xiang-Rui; Rao, Weidong; Xu, Haiyan; Shen, Zhi-Liang. Application of 16629-19-9 And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

A facile incorporation of a privileged sulfide, naphthofurans e.g., 2-(perfluoroethyl)-3-(p-tolylthio)naphtho[1,2-b]furan framework, and a perfluoroalkyl moiety in one mol. was successfully accomplished through tandem defluorinative sulfenylation of α-perfluoroalkyl ketones e.g., 2-(Perfluorobutyl)-3,4-dihydronaphthalen-1(2H)-one with a sulfur source RS(O)ONa/RS(O)OCl (R = Ph, naphthalen-1-yl, thiophen-2-yl, etc.). The reaction presumably proceeds via a sequence involving defluorination, reductive sulfenylation, autoaromatization, and annulation, accompanied by the simultaneous cleavage of four C(sp3)-F bonds and the formation of new C-S and C-O bonds. The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Application of 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Application of 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Pd-catalyzed amidation of 1,3-diketones with CO and azides via a nitrene intermediate》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Gu, Zheng-Yang; Chen, Jie; Xia, Ji-Bao. Computed Properties of C4H3ClO2S2 The article mentions the following:

An efficient Pd-catalyzed amidation of 1,3-diketones has been developed using carbon monoxide and organic azides. This reaction provides a step-economic approach to produce β-ketoamides from readily available compounds under mild ligand-, oxidant-, and base-free conditions. The mechanistic studies showed that the reaction occurred through an in situ generated isocyanate intermediate. The experimental part of the paper was very detailed, including the reaction process of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Computed Properties of C4H3ClO2S2)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Computed Properties of C4H3ClO2S2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Jiang, Yi-Min; Yu, Yi; Wu, Shao-Fen; Yan, Hong; Yuan, Yaofeng; Ye, Ke-Yin published an article in 2021. The article was titled 《Electrochemical fluorosulfonylation of styrenes》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Quality Control of Thiophene-2-sulfonyl chloride The information in the text is summarized as follows:

An environmentally friendly and efficient electrochem. fluorosulfonylation of styrenes were developed. With the use of sulfonylhydrazides and triethylamine trihydrofluoride, a diverse array of β-fluorosulfones were readily obtained. This reaction featured mild conditions and a broad substrate scope, which was conveniently extended to a gram-scale preparation In the experiment, the researchers used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Quality Control of Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Quality Control of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Electrochemical heterodifunctionalization of α-CF3 alkenes to access α-trifluoromethyl-β-sulfonyl tertiary alcohols》 was written by Ye, Zhi-Peng; Gao, Jie; Duan, Xin-Yu; Guan, Jian-Ping; Liu, Fang; Chen, Kai; Xiao, Jun-An; Xiang, Hao-Yue; Yang, Hua. Application In Synthesis of Thiophene-2-sulfonyl chlorideThis research focused ontrifluoromethyl sulfonyl tertiary alc green preparation; benzenesulfonyl hydrazide trifluoromethyl alkene electrochem heterodifunctionalization. The article conveys some information:

An unprecedented electrochem. heterodifunctionalization of α-CF3 alkenes with benzenesulfonyl hydrazides was accomplished in this work, wherein a β-sulfonyl and a α-hydroxyl group were simultaneously incorporated across the olefinic double bond in a single operation. Consequently, a series of potentially medicinally valuable and densely functionalized α-trifluoromethyl-β-sulfonyl tertiary alcs. RSOOCH2C(OH)(CF3)R1 [R = i-Pr, Ph, 2-thienyl, etc.; R1 = Ph, 2-naphthyl, 3-thienyl, etc.] were assembled under mild conditions. Electrochem.-driven oxidative 1,2-difunctionalization of electron-deficient alkenes well obviates the need for oxidizing reagents, thus rendering this protocol more eco-friendly. In addition to this study using Thiophene-2-sulfonyl chloride, there are many other studies that have used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Application In Synthesis of Thiophene-2-sulfonyl chloride) was used in this study.

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Application In Synthesis of Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《A visible light-mediated, decarboxylative, desulfonylative Smiles rearrangement for general arylethylamines syntheses》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Whalley, David M.; Duong, Hung A.; Greaney, Michael F.. Synthetic Route of C4H3ClO2S2 The article mentions the following:

A decarboxylative, desulfonylative Smiles rearrangement is presented that employs activated-ester/energy transfer catalysis to decarboxylate β-amino acid derived starting materials at room-temperature under visible light irradiation The radical Smiles rearrangement gives a range of biol. active arylethylamine products highly relevant to the pharmaceutical industry, chem. biol. and materials science. The reaction is then applied to the synthesis of a chiral unnatural amino acid, 2-thienylalanine, used in the treatment of phenylketonuria. It was also shown how the reaction can proceed under metal-free and catalyst-free conditions. The experimental part of the paper was very detailed, including the reaction process of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Synthetic Route of C4H3ClO2S2)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Synthetic Route of C4H3ClO2S2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics