Category: 18791-02-1

Binisti, Carine published the artcileStructure-activity relationships in platelet activating factor. 9. From PAF-antagonism to PLA₂ inhibition, Synthetic Route of 18791-02-1, the publication is Journal of Lipid Mediators and Cell Signalling (1997), 15(2), 125-144, database is CAplus and MEDLINE.

Novel acylated piperazines substituted at the 2-position by C_4-17 alkyl groups, analogs of known PAF-antagonists, were prepared by standard methods. These new compounds inhibited various secretory PLA₂s, with IC₅₀‘s in the μmol range. SAR evaluation showed that inhibition of secretory PLA₂ depends on the length of the alkyl chain, with an optimum for 13 to 17 carbons, which is in agreement with X-ray crystallog. and NMR (NMR) studies on the active site of PLA₂s, and that a free nitrogen on the piperazine ring is required to ensure a good inhibitory potency.

Journal of Lipid Mediators and Cell Signalling published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Synthetic Route of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Hashimura, Kazuya published the artcileA stereocontrolled route to both enantiomers of the necine base dihydroxyheliotridane via intramolecular 1,3-dipolar addition using the same chiral precursor, Related Products of chlorides-buliding-blocks, the publication is Journal of the Chemical Society, Chemical Communications (1995), 2291-2, database is CAplus.

Diastereofacial selectivity in an enantiospecific intramol. 1,3-dipolar addition is controlled by adjusting the size of the tether between the dipole and the dipolarophile to give 2,3-disubstituted pyrrolidines enantiomeric with respect to the newly generated stereogenic 2,3-centers depending on the tether size; this leads to stereocontrolled synthesis of the (-)-(I) and (+)-enantiomers of the necine base dihydroxyheliotridane from chiral O-benzylglycidol.

Journal of the Chemical Society, Chemical Communications published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Phillips, Duncan A. S. published the artcileThe dyeing performance on cotton of reactive dyes containing the α-bromoacrylamido group, Related Products of chlorides-buliding-blocks, the publication is Dyes and Pigments (1999), 43(2), 153-160, database is CAplus.

Three reactive azo dyes containing the α-bromoacrylamido group have been synthesized and their performance assessed for the exhaust dyeing of cotton. The results indicate that, when situated in the appropriate electronic environment in the dye mol., this reactive group is compatible with the sulfatoethylsulfonyl (vinylsulfonyl) group in delivering warm dyeing (60°C) characteristics.

Dyes and Pigments published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Rhee, Sung W. published the artcileSynthesis of tritium labeled 4P-PDOT, a selective melatonin receptor antagonist, Quality Control of 18791-02-1, the publication is Journal of Labelled Compounds & Radiopharmaceuticals (2000), 43(9), 925-932, database is CAplus.

A selective MT2 melatonin receptor antagonist, 4-phenyl-2-propionamidotetralin (4P-PDOT), was prepared as a tritium-labeled compound with high specific activity and radiochem. purity. Catalytic hydrogenation of a unique vinyl bromo precursor was used to introduce the tritium.

Journal of Labelled Compounds & Radiopharmaceuticals published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Quality Control of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Khare, R. K. published the artcileSynthesis and fungicidal activity of some 5-methylene-2-[5′-aryl-1′,3′,4′-oxa(thia)diazol-2′-yl]amino-4-thiazolones, Computed Properties of 18791-02-1, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1995), 34B(9), 828-31, database is CAplus.

N¹-(5-aryl-1,3,4-oxa(thia)diazol-2-yl)thioureas undergo regioselective cyclocondensation with 2,3-dibromopropionyl chloride to give 5-methylene-2-[5′-aryl-1′,3′,4′-oxa(thia)diazol-2′-yl]amino-4-thiazolones. These thiazolones have been tested in vitro for their antifungal activity against Aspergillus niger and Fusarium oxysporium and results compared with their parent thioureas. Attempts have also been made to correlate structural features of tested compounds with their activity.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Balaganesh, Muthiah published the artcilePhotodissociation of CH₂BrCHBrC(O)Cl at 248 nm: probing Br₂ as the primary fragment using cavity ring-down spectroscopy, Name: 2,3-Dibromopropionylchloride, the publication is Physical Chemistry Chemical Physics (2021), 23(39), 22492-22500, database is CAplus and MEDLINE.

The photodissociation of 2,3-dibromopropionyl chloride (CH₂BrCHBrC(O)Cl, 2,3-DBPC) at 248 nm was carried out to study Br₂ as the primary mol. product in the B³Î ⁺_0u â†?X¹Î£⁺_g transition using cavity ring-down absorption spectroscopy. The rotational spectra (v” = 0-2) were acquired and assigned with the aid of spectral simulation. It is verified that the obtained Br2 fragment is attributed to the one-photon dissociation of 2,3-DBPC and is free from contributions of secondary reactions. The vibrational ratio of the Br2 population of v(0):v(1):v(2) is equal to 1:(0.58 ± 0.12):(0.23 ± 0.09), corresponding to the Boltzmann vibrational temperature of 623 ± 38 K. The quantum yield of Br₂ eliminated from 2,3-DBPC is estimated to be 0.09 ± 0.04. The dissociation pathways of 2,3-DBPC and its potential energy surfaces were calculated using d. functional theory. By employing the CCSD(T)//M062X/6-31+g(d,p) level of theory, transition state barriers and corresponding reaction energies were calculated for the Br, Cl, Br₂, BrCl, HBr and HCl elimination channels. The unimol. rate constant for Br₂ elimination was determined to be 2.09 x 10⁵ s^-1 using Rice-Ramsperger-Kassel-Marcus (RRKM) theory, thus explaining the small quantum yield of the Br₂ channel.

Physical Chemistry Chemical Physics published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Name: 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Kim, Tae-Kyung published the artcileSynthesis of a novel bridge compound having hetero-bi-functional reactive groups. Part 1: its adsorption properties, HPLC of Formula: 18791-02-1, the publication is Dyes and Pigments (2005), 65(3), 261-266, database is CAplus.

A novel heterobifunctional compound containing two different reactive groups, α,β-dibromopropionylamino and dichloro-s-triazinyl groups, was synthesized. The α,β-dibromopropionylamino group had considerable reactivity towards amines or amino groups under acidic conditions and high temperature The dichloro-s-triazinyl group had reactivity towards hydroxyl groups under alk. conditions and room temperature The compound was used as a bridge to fix dyes containing amino groups (e.g. 1-amino-4-hydroxyanthraquinone) to cellulosic substrates (e.g. cotton textiles). The effects of temperature, pH, neutral salt, treatment time and concentration on chemisorption of the bridge compound to cotton fibers were investigated. The heterobifunctional compound provided the 1-amino-4-hydroxyanthraquinone-dyed cotton textile with a color strength of 14.73, while the dyed untreated textile had a color strength of 0.78.

Dyes and Pigments published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, HPLC of Formula: 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Tomashevskii, A. A. published the artcileReaction of (α-haloalkyl)thiiranes with nucleophilic reagents. I. Reaction with morpholine, HPLC of Formula: 18791-02-1, the publication is Zhurnal Organicheskoi Khimii (1994), 30(10), 1528-36, database is CAplus.

D-labeling experiments showed that (chloromethyl)thiirane reacts with morpholine by a mechanism involving initial ring cleavage and subsequent recyclization. In the case of (bromomethyl)thiirane, direct substitution of Br competes with this mechanism. Reactions of morpholine with 2-(chloromethyl)-2-methylthiirane, 3-(chloromethyl)-2,2-dimethylthiirane, and diastereoisomers of (1-chloroethyl)thiirane were also examined

Zhurnal Organicheskoi Khimii published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C5H5BrN2, HPLC of Formula: 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ruefenacht, Kurt published the artcilePhosphoric acid esters and thiophosphoric acid esters with some heterocyclic substitutions. 7. Thio- and dithiophosphoric acid esters of the GS 13005 type with some analog or homolog heterocyclic rings, Product Details of C3H3Br2ClO, the publication is Helvetica Chimica Acta (1973), 56(7), 2186-204, database is CAplus.

Analogs of the pesticide GS 13005 were prepared, including pyrazolinones of the type I, (R = Cl, OH), pyrazoles II, (R = H, Me, Cl; R1 = H, Cl, Br, NO2; R2 = H, Me, iso-Pr; R3 = Cl, OH), pyridazinones III, (R = H, Cl, Br, Me, Et; R1 = H, Cl, Me; R2 = H, Cl, Me; R3 = Cl, OH), thiadiazinones IV, (R = Me, Et; R1 = Cl, OH), and their mono- and dithiophosphates. The preparation, of analogous thiadiazepinones failed, giving instead pyrazolidinone derivatives Approx. 100 compounds were prepared

Helvetica Chimica Acta published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Product Details of C3H3Br2ClO.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Mao, Faming published the artcileSynthesis of reactive scarlet 3G, Category: chlorides-buliding-blocks, the publication is Ranliao Yu Ranse (2010), 47(1), 19-20, database is CAplus.

Reactive scarlet 3G was prepared from sodium 2,4-diaminobenzenesulfonate, 2,3-dibromopropanoyl chloride and γ acid by acylation, diazotization, coupling and salting-out. The two steps of acylation were studied emphatically. The complete reaction conditions were obtained by experiments: the temperature of acylation was 0-15°C, pH was controlled between 5-7.5; the molar ratio of 2, 3-dibromopropanoyl chloride and sodium 2,4-diaminobenzenesulfonate was 1.05: 1,2,3-dibromopropanoyl chloride and γ acid molar ratio was 1.05: 1. The yield of acylation was above 90%.

Ranliao Yu Ranse published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics