Category: 18791-02-1

Li, Xuemin published the artcileQuantitative analysis of 2,3-dibromopropionyl chloride, Application of 2,3-Dibromopropionylchloride, the publication is Ranliao Yu Ranse (2011), 48(6), 56-59, database is CAplus.

An anal. method for a dye intermediate 2,3-dibromopropionyl chloride was established. The method was based on derivation of 2,3-dibromopropionyl chloride. 2,3-Dibromo-N-phenylpropanamide was almost quant. prepared from 2,3-dibromopropionyl chloride and aniline by amidation. The external standard calibration curve of 2,3-dibromo-N-phenylpropanamide was obtained by HPLC, thus the content of 2,3-dibromopropionyl chloride was determined The linear regression equation of the method was given, the liner correlation coefficient was 0.9997, the linear range was 0.1341-0.6707 mg/mL, the standard deviation was 0.005, the variation coefficient was 0.5%, and the recovery rate was 99.81%-100.05%.

Ranliao Yu Ranse published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Application of 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Okawara, Tadashi published the artcileSynthesis of new uracils having N-amino-β-, -γ-, and -δ-lactams, COA of Formula: C3H3Br2ClO, the publication is Heterocycles (1988), 27(8), 1881-5, database is CAplus.

The reaction of 1,3-dimethyl-6-methylhydrazinouracil with R(CH₂)_nCR¹R²COCl (R = Br, Cl; R¹,R² = H, Me, Br; n = 1-5) afforded N-haloacylhydrazinouracils I, which were converted into the lactams II by treatment with KOH in the presence of TEBAC.

Heterocycles published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, COA of Formula: C3H3Br2ClO.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Comstock, Lindsay R. published the artcileExpeditious synthesis of aziridine-based cofactor mimics, Name: 2,3-Dibromopropionylchloride, the publication is Tetrahedron (2002), 58(30), 6019-6026, database is CAplus.

S-Adenosyl-L-methionine mimics were synthesized in a linear fashion highlighting methodol. that bypasses the need for adenine base protection. These aziridine-based cofactor mimics are envisioned as useful biochem. tools and potential therapeutic agents whose mechanism of action hinges upon aberrant methyltransferase enzymes. Aziridination of the 5′ position of adenosine was effected by convergence of suitably protected 5′-aminoadenosine with various dibromopropionates. The economy and high yields for this route to said aziridine-based cofactors is highly amenable to large-scale chem. which no doubt will be vital to their development as therapeutics and biochem. tools.

Tetrahedron published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Name: 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Eremeev, A. V. published the artcileAsymmetric unbridged nitrogen. 37. Absolute configuration of diastereomeric derivatives of N-substituted aziridine-2-carboxylic acids, Computed Properties of 18791-02-1, the publication is Khimiya Geterotsiklicheskikh Soedinenii (1984), 1343-8, database is CAplus.

Both (R,S)- and (S,S)-aziridinecarboxanilides (I; R, R¹ = Me, H; Me, Br; CHMe₂, Br) were prepared and the diastereoisomers distinguished by their ¹H and ¹⁵N NMR and CD spectra.

Khimiya Geterotsiklicheskikh Soedinenii published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Jones, F. William published the artcileFiber-reactive insect-resist agents for wool: the synthesis and effectiveness of some organophosphorus compounds, Related Products of chlorides-buliding-blocks, the publication is Pesticide Science (1982), 13(6), 602-10, database is CAplus.

Fiber-reactive derivatives of 10 organophosphorus compounds were synthesized and evaluated as insect-resistant agents for wool. Some were very effective against wool pests and, when the fiber-reactive group was a 2-bromoacrylic ester group, these compounds also exhibited good fastness to washing and dry-cleaning.

Pesticide Science published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Okawara, Tadashi published the artcileA facile synthesis of thiazolidin-5-ones and their structural assignment, SDS of cas: 18791-02-1, the publication is Heterocycles (1982), 19(9), 1571-4, database is CAplus.

RNHCSNHR¹ (R = CH₂Ph, Me, Ph; R¹ = CH₂Ph, Ph) reacted with R²CHR³COR³ (R² = H, Me, R³ = halogen) in 5% NaOH-CH₂Cl₂ to give 34-89% iminothiazolidinones I. Reaction of RNHCSNHR¹ with BrCH₂CHBrCOCl gave 75 to 83% II.

Heterocycles published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, SDS of cas: 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Takano, Seiichi published the artcileChiral synthesis of both enantiomers of 1,4-dideoxy-1,4-iminolyxitol and 1,4-dideoxy-1,4-iminoribitol, Synthetic Route of 18791-02-1, the publication is Tetrahedron: Asymmetry (1992), 3(6), 681-4, database is CAplus.

Reaction of 2,3-dibromopropionyl chloride with 4-methoxyphenol and (S)-1-methylbenzylamine yielded a 4:5 mixture of readily separable diastereomeric aziridine esters I (R = C₆H₄OMe-4) in an excellent yield. Thermal intermol. 1,3-dipolar cycloaddition of both diastereomers with vinylene carbonate, furnished four readily separable diastereomeric pyrrolidine esters, resp., which were transformed into both enantiomers of title compounds

Tetrahedron: Asymmetry published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C14H22O2, Synthetic Route of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Hayashi, Koichiro published the artcileChemoselective Synthesis of Folic Acid-Functionalized Magnetite Nanoparticles via Click Chemistry for Magnetic Hyperthermia, HPLC of Formula: 18791-02-1, the publication is Chemistry of Materials (2009), 21(7), 1318-1325, database is CAplus.

Folic acid-functionalized Fe₃O₄ nanoparticles (FA-Fe₃O₄ NPs) were synthesized from iron(III) 3-allylacetylacetonate (IAA) through in situ hydrolysis and ligand modification, by applying the principle of click chem. The γ-carboxylic acid of FA was successfully bound to the ligand of the Fe₃O₄ NPs without the loss of the α-carboxylic acid group of folic acid (FA), which has an affinity for folate receptors (FRs) expressed on tumor cells. The Fe₃O₄ NPs were monodisperse, and their size was controlled by varying the conditions of IAA hydrolysis. The FA-Fe₃O₄ NPs, which had diameters of 8 nm, exhibited superparamagnetic behavior and a relatively high magnetization at room temperature The blocking temperature is 220 K, and the magnetization curve exhibited a remanence of 19 emu/g and a coercivity of 550 Oe at 5 K. The specific absorption rate (SAR) was dependent on the size of the FA-Fe₃O₄ NPs and the strength of the applied magnetic field. The SAR of the 8-nm FA-Fe₃O₄ NPs was 670 W/g in a 230 kHz alternating magnetic field and 100 Oe. The chemoselective surface modification of magnetite particles with FA yielded a novel cancer-targeting system for use in hyperthermia treatment.

Chemistry of Materials published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, HPLC of Formula: 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Joyeau, Roger published the artcileN-Aryl 3-halogenated azetidin-2-ones and benzocarbacephems, inhibitors of β-lactamases, HPLC of Formula: 18791-02-1, the publication is Journal of Medicinal Chemistry (1988), 31(2), 370-4, database is CAplus and MEDLINE.

N-Aryl-3-haloazetidinones I (R = F, R¹ = H, F, Br; R = Br, R¹ = H, Br) were prepared by amidating BrCH₂CRR¹COCl, ring closure of BrCH₂CRR¹CONHC₆H₃(Me)CO₂CMe₃-2,5, and ester hydrolysis. Their affinities for the TEM-1 β-lactamase were determined and compared with those of the benzocarbacephems II (R² = H, Cl, F), and known β-lactamase inhibitors. I and II behave as competitive inhibitors and not as substrates of the enzyme; neither halogen substitution nor ring strain induces enzymic hydrolysis.

Journal of Medicinal Chemistry published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, HPLC of Formula: 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Safonova, T. S. published the artcileRelation of the antitumor activity of spirobromine analogs to their structure, Application of 2,3-Dibromopropionylchloride, the publication is Khimiko-Farmatsevticheskii Zhurnal (1984), 18(12), 1437-40, database is CAplus.

The dispiropiperazines I [R = CHBrCH₂Br, CH:CH₂, CHMeCH₂Br, CH₂CH₂NHCH₂Ph, (CH₂)₃Ph, (CH₂)₃C₆H₄NO₂–p, and (CH₂)₃C₆H₄N(CH₂CH₂Cl)₂–p] were prepared and tested along with spirobromine (I, R = CH₂CH₂Br) [86641-76-1] and 8 dipiperazinylalkanes II (R = Me, H; X = Cl, Br; n = 2, 3, 6, 10) for antitumor activity in sarcoma-bearing rats. Although spirobromine itself showed high antitumor activity, its analogs were only ∼33% as active or completely inactive. Three dipiperazinylalkanes showed very high activity; the others were inactive. Structure-activity relations are discussed.

Khimiko-Farmatsevticheskii Zhurnal published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Application of 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics