Category: 18791-02-1

Okawara, Tadashi published the artcileConvenient syntheses of cyclic carboxamides from α,β,γ,δ and ε-halocarboxamides under phase transfer conditions, COA of Formula: C3H3Br2ClO, the publication is Chemical & Pharmaceutical Bulletin (1982), 30(4), 1225-33, database is CAplus.

Piperazine-2,5-diones I (R = H, Me; R¹ = PhCH₂, Ph) were prepared by N-alkylation between two mols. of α-halocarboxamides RCHXCONHR¹ (same R, R¹; X = Cl, Br) in the presence of a phase transfer catalyst in yields of 64-88%. II (R=H, Me; R¹=H, Me, Br; R²=Ph, PhCH₂), III (Q= CH₂CH₂, o-, m-, and p-phenylene, p-C₆H₄SO₂C₆H₄–p), IV (R= H, Me; R¹= PhCH₂, Ph; n=1,2,3) were similarly synthesized by intramol. N-alkylation of the corresponding halocarboxamides under phase transfer conditions in 53-99 % yields.

Chemical & Pharmaceutical Bulletin published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, COA of Formula: C3H3Br2ClO.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Saunders, K. G. published the artcilePoly(alkyl α-bromoacrylates). 2. Preparation and properties of the methyl, ethyl, n-propyl, isopropyl, n-butyl, and n-pentyl esters of varied tacticity, Computed Properties of 18791-02-1, the publication is Macromolecules (1982), 15(1), 1-10, database is CAplus.

Polymers of widely ranging tacticities, from highly isotactic to highly syndiotactic, were synthesized from Me [4519-46-4], Et [5459-35-8], Pr [13401-88-2], iso-Pr [79762-79-1], Bu [6420-76-4], and n-pentyl α-bromoacrylate  [13401-89-3]. The isotactic polymers were synthesized with a modified Grignard complex consisting a Grignard reagent and benzalacetophenone  [94-41-7]. A low-temperature, photolytically induced, free radical polymerization reaction was employed for the preparation of the syndiotactic polymers. Only atactic poly(tert-Bu α-bromoacrylate) [79794-49-3] could be synthesized because of the failure of the corresponding monomer to polymerize with the modified Grignard complex or at temperatures <20°. Polymer tacticity was determined by 19-Hz ¹³C NMR spectroscopy. Complete assignments for the ten pentad peaks of the carbonyl carbon resonance were achieved for all but the iso-Pr ester polymer while a complete anal. of the tetrad tacticity for the backbone methylene carbon resonance was possible for all but the Me ester polymer. The polymerization reaction mechanisms were discussed in terms of the propagation statistics which were calculated from the exptl. tetrads and pentads.

Macromolecules published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Hrdina, R. published the artcileIron complexes of reactive azo dyes, Related Products of chlorides-buliding-blocks, the publication is Advances in Colour Science and Technology (2004), 7(1), 6-17, database is CAplus.

A set of reactive mordant azo dyes was prepared by diazotization of aromatic amines and their subsequent coupling reaction with secondary components. The reactive dyes thus formed contained 2-sulfatoethylsulfonyl (-SO₂CH₂CH₂OSO₃Na), N-methyl-N-carboxymethyl-2-aminoethylsulfonyl (-SO₂CH₂CH₂NMeCH₂CO₂H) and 2,3-dibromopropionamidyl (-NHCOCHBrCH₂Br) reactive groups capable of liberating reactive vinyl groups in the application dyebath. Neg.-ion electrospray ionization mass spectrometry, UV/visible spectroscopy, and elemental anal. confirmed the structure of the prepared dyes. Dyed wool fabric samples (combination of acid and reactive dyeing conditions) were treated (mordanted) with iron salts (FeCl₂, FeCl₃) and a comparison chromium salt (CrF₃). The iron mordant dyeing showed acceptable wash fastness and light fastness comparable with chromium complexed dyes.

Advances in Colour Science and Technology published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Adams, H. Jack published the artcilePrimary local anesthetic testing and acute toxicity of N,N’-disubstituted 2,3-diamino-2′,6′-propionoxylidides, SDS of cas: 18791-02-1, the publication is Journal of Pharmaceutical Sciences (1973), 62(10), 1677-9, database is CAplus and MEDLINE.

The local anesthetic activity of the 8 N,N’-disubstituted-2,3-diamino-2′,6′-propionoxylidides (I) and 1-tert-butyl-2-aziridinecarboxy-2′,6′-xylidide (II) [50603-33-3] which were prepared fell between that of lidocaine-HCl [73-78-9] and tetracaine-HCl [136-47-0]. None of the compounds possessed the long duration of tetracaine in the guinea pig wheal. All the compds were more toxic than tetracaine i.p. in the mouse and except for II they were less irritating than tetracaine in the rabbit intradermal wheal.

Journal of Pharmaceutical Sciences published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, SDS of cas: 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Silina, E. B. published the artcileα-Bromoalkyl isocyanates and their phosphorylated derivatives, Computed Properties of 18791-02-1, the publication is Zhurnal Obshchei Khimii (1989), 59(3), 571-86, database is CAplus.

Reaction of Br₃CNCO with ROPX₂ (R = Me, Et, X = Cl; R = Bu, X = F) in the presence of FeCl₃ gave 27-58% X₂P(O)CBr₂NCO. Arbuzov reaction of BrCH₂CHBrNCO with (R¹O)₃P (R¹ = Et, Me) or with halophosphites (EtO)₂PX (X = Cl, F) or EtOPX₂ (X = Cl, F) gave (R¹O)₂P(O)CH(CH₂Br)NCO (I; same R¹), 40-60% EtOPX(O)CH(CH₂Br)NCO (II; same X), or 54-72% X₂P(O)CH(CH₂Br)NCO (III; same X), resp. Treating I (R¹ = Et) and II–III with Et₃N gave 48-75% ethylene isocyanates (EtO)_n(X)_2-nP(O)C(:CH₂)NCO (IV; n = 0-2; X = Cl, F), which when treated with Br₂ gave 33-68% (EtO)_n(X)_2-nP(O)CBr(CH₂Br)NCO (V). Reaction of III (X = Cl) or IV (n = 0; X = Cl) with R²OH (R² = Me, Et) and Et₃N gave 73-87% carbamates (R²O)₂P(O)C(:CH₂) NHCO₂R. III (X = F) and IV (n = 0, X = F) reacted with PhNH₂ to give 65-81% anilides F₂P(O)CH(CH₂Br)NHCONHPh and F₂P(O)C(:CH₂)NHCONHPh, resp. ¹H, ¹⁹F, and ³¹P NMR spectra of III–V are discussed.

Zhurnal Obshchei Khimii published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C10H9N3O, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Oh, Myung J. published the artcileComparison of the resist effectiveness and leveling character of α-bromoacrylamide based and 2,4-dichloro-s-triazine based dye-resist agents for wool, Name: 2,3-Dibromopropionylchloride, the publication is Dyes and Pigments (2005), 70(3), 220-225, database is CAplus.

Three dye resists based on α-bromoacrylamide and three dye resists based on dichlorotriazine were synthesized and their effectiveness and leveling properties were compared on wool. In general, the dichlorotriazine based resist agents displayed higher resist effectiveness in dyeing than their α-bromoacrylamide counterparts. However, the resists based on α-bromoacrylamide exhibited better leveling properties than those based on dichlorotriazine. The resist effectiveness was significantly improved by increasing the number of sulfonate group in the dye-resist agents and the hydrophilic character of anionic dyes applied over them.

Dyes and Pigments published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Name: 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Kochetkov, N. K. published the artcileCycloserine and related compounds. VIII. Synthesis of 3-isoxazolidones, Category: chlorides-buliding-blocks, the publication is Zhurnal Obshchei Khimii (1959), 3417-24, database is CAplus.

cf. CA 54, 8777i. Halo hydroxamic acids were prepared by a general reaction of acyl chlorides with H₂NOH in aqueous medium, the products being cyclized to 3-isoxazolidones by MeOH-KOH. To 32 g. NaOH in 120 ml. H₂O was added at 0° 55.5 g. NH₂OH.HCl and the resulting solution was treated below 5° with 68.6 g. BrCH₂CH₂COCl. After 1 hr. at 0-5°, 1.5 hrs. at 15°, the mixture was heated to 60° and filtered. The filtrate after 1-2 days at -5° gave 48-50% BrCH₂CH₂CONHOH (I), m. 88-90°. Similarly were prepared: 50-5% ClCH₂CH₂CONHOH, m. 102-4°; 52-5% BrCH₂CHMeCONHOH, m. 98-100°; 61% PhCHBrCH₂CONHOH, m. 85-90°; 65% ClCMe₂CH₂CONHOH, an oil; PhCH:CPhCONHOH (from PhCHBrCHPhCOCl), 50%, m. 147-9°; BrCH₂CHBrCONHOH, 55-60%, m. 151-3°: 50-60% ClCH₂CHClCONHOH, m. 95-7°. I (6.8 g.) in 15 ml. MeOH was treated with 40 ml. 2N MeOH-KOH and heated 40 min., yielding after filtration and evaporation and treatment of the residue with Et₂O 80-5% K salt of 3-isoxazolidone, decomposed 213-15°, which with aqueous AgNO₃ gave the Ag salt, decomposed 166-8°. The K salt treated with absolute EtOH-HCl gave 70% 3-isoxazolidone, m. 69-70°. Similarly, were prepared: 70% K salt of 4-methyl-3-isoxazolidone, decomposed 151-3° (free base decomposed 72-4°); 70% K salt of 5-phenyl-3-isoxazolidone, decomposed 285-7° (free base m. 121-3°); 50% K salt of 5,5-dimethyl-3-isoxazolidone, m. 122-5° (Ag salt, decomposed 166-8°; free base, an unpurifiable oil). The K salt of 3-isoxazolidone and BzCl in dioxane gave 47% N-benzoyl-3-isoxazolidone, m. 123-4°, also formed from the Ag salt in 40% yield. Similarly were prepared: 51% N-(p-nitrobenzoyl)-3 isoxazolidone, m. 178-80°, and 40% N-carbomethoxy-3-isoxazolidone, m. 106-8°.

Zhurnal Obshchei Khimii published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Oh, Myung Joon published the artcileSynthesis of heteromultifunctional dyeresist agents containing chloro-s-triazine and α-bromoacrylamide and their dyeresist properties in wool fabrics, Safety of 2,3-Dibromopropionylchloride, the publication is Coloration Technology (2006), 122(4), 227-232, database is CAplus.

Five heteromultifunctional dye-resist agents containing chloro-s-triazine and α-bromoacrylamide were synthesized and their resist effectiveness on wool were compared. The dye-resist agent with the dichlorotriazinyl group showed better resist effectiveness than the dye-resist agent with the monochlorotriazinyl group. Also, their resist effectiveness was improved by increasing the number of sulfonate groups in the dye-resist agents and the reactive groups in the reactive dyes applied over them.

Coloration Technology published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Safety of 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Kim, Kwang Soo published the artcileDyeing properties of reactive disperse dye having bromoacrylamide group, Application In Synthesis of 18791-02-1, the publication is Journal of the Korean Fiber Society (2001), 38(12), 683-692, database is CAplus.

A reactive disperse azo dye having an α-bromoacrylamido group was synthesized and its dyeing and fastness properties were compared with those of a a disperse dye. The amount of absorbed reactive disperse dye was less on polyester fabric than the disperse dye, and was much higher on nylon fabric. When polyester and nylon fiber were simultaneously dyed, the nylon absorbed more reactive disperse dye than polyester. The use of a carrier or a variation of dyebath pH was not able to provide the same color depth on both fibers. A nylon/polyester union fabric could be dyed with the reactive disperse dye and the color fastness was good to excellent.

Journal of the Korean Fiber Society published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Application In Synthesis of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

DeShong, Philip published the artcileIntermolecular and intramolecular azomethine ylide [3 + 2] dipolar cycloadditions for the synthesis of highly functionalized pyrroles and pyrrolidines, Safety of 2,3-Dibromopropionylchloride, the publication is Journal of Organic Chemistry (1985), 50(13), 2309-15, database is CAplus.

N-Alkyl and N-arylaziridines carrying a single carboxy ester function, e.g., I, undergo thermally induced electrocyclic ring opening to produce azomethine ylides, which subsequently react with acetylenes or olefins to yield substituted pyrroles, e.g., II, or pyrrolidines, e.g., III, resp. The [3 + 2] dipolar cycloaddition reaction can be performed in either an intermol. or intramol. mode and displays high regioselectivity and stereoselectivity with a variety of dipolarophiles. The yield of cycloadducts depends on the electronic characteristics and the substitution pattern of the dipolarophile, and on the mode of cycloaddition employed. In the intermol. reaction, the yield of adducts is poor unless the dipolarophile is activated. Intramol. cycloadditions with monosubstituted olefins or acetylenes give adducts in yields of 45-70%. Although the yields of adducts in these instances are moderate, the starting materials are readily prepared and the method is an effective means for the assembly of a structurally complex heterocyclic system with high regiochem. and stereochem. control of peripheral substituents. When the dipolarophilic component is disubstituted, the cycloaddition gives synthetically useful yields if the dipolarophile carries an electron-withdrawing functionality.

Journal of Organic Chemistry published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Safety of 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics